CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) - BSA Free

Novus Biologicals | Catalog # NBP2-50150

Novus Biologicals

Key Product Details

Species Reactivity

Mouse

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Functional, CyTOF-ready

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # TAN 1-7

Format

BSA Free
View all CD27 Ligand/TNFSF7 Primary Antibodies »

Product Specifications

Immunogen

Recombinant mouse CD27 Ligand/TNFSF7/CD70 (extracellular domain, aa residues 41-195)

Specificity

This antibody is a non-depleting mAb that blocks the CD70-CD27 interaction.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Description

Novus Biologicals Rat CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) - BSA Free (NBP2-50150) is a monoclonal antibody validated for use in ELISA, Flow and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Applications for CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Flow Cytometry

1:10 - 1:1000

Immunocytochemistry/ Immunofluorescence

1:10 - 1:500
Application Notes
This antibody is a non-depleting monoclonal antibody that blocks the CD70-CD27 interaction. This antibody is Cytof ready. Positive control(s): Activated dendritic cells.

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD27 Ligand/TNFSF7

CD70 is a type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. The FR70 antibody blocks CD70 binding to CD27.

Alternate Names

CD70, TNFSF7

Gene Symbol

CD70

Additional CD27 Ligand/TNFSF7 Products

Product Documents for CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) - BSA Free

Certificate of Analysis

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Product Specific Notices for CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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