CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) [DyLight 488]

Novus Biologicals | Catalog # NBP2-50150G

Novus Biologicals
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Key Product Details

Species Reactivity

Mouse

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Functional, CyTOF-ready

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Rat IgG2A Clone # TAN 1-7
View all CD27 Ligand/TNFSF7 Primary Antibodies »

Product Specifications

Immunogen

Recombinant mouse CD27 Ligand/TNFSF7/CD70 (extracellular domain, aa residues 41-195)

Specificity

This antibody is a non-depleting mAb that blocks the CD70-CD27 interaction.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Description

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Applications for CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) [DyLight 488]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Spectra Viewer

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CD27 Ligand/TNFSF7

CD70 is a type II transmembrane protein. It is a member of the TNF superfamily, expressed on activated B cells, activated dendritic cells, and some activated T cells (low levels). CD70 interacts with CD27 to promote T-B cell cross-stimulation and co-stimulate B cell proliferation and immunoglobulin production. Cells expressing CD70 can co-stimulate T cell proliferation and enhance the production of cytokines. The FR70 antibody blocks CD70 binding to CD27.

Alternate Names

CD70, TNFSF7

Gene Symbol

CD70

Additional CD27 Ligand/TNFSF7 Products

Product Documents for CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) [DyLight 488]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for CD27 Ligand/TNFSF7/CD70 Antibody (TAN 1-7) [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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