Compound W

Catalog # Availability Size / Price Qty
Compound W | CAS No. 173550-33-9 | Secretase Inhibitors
1 Image
Description: γ-secretase inhibitor
Alternative Names: CW

Chemical Name: 3,5-Bis(4-nitrophenoxy)benzoic acid

Purity: ≥99%

Product Details
Citations (2)

Biological Activity

Compound W is an inhibitor of γ-secretase; causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).

Technical Data

Soluble to 50 mM in 1.1eq. NaOH and to 100 mM in DMSO
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Secretion of the notch-1 Aβ-like peptide during notch signaling.
    Okochi et al.
    J.Biol.Chem., 2006;281:7890

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for Compound W

The citations listed below are publications that use Tocris products. Selected citations for Compound W include:

2 Citations: Showing 1 - 2


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