Chemical Name: 3,5-Bis(4-nitrophenoxy)benzoic acid
Biological ActivityCompound W is an inhibitor of γ-secretase; causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Secretion of the notch-1 Aβ-like peptide during notch signaling.
Okochi et al.
Citations for Compound W
The citations listed below are publications that use Tocris products. Selected citations for Compound W include:
2 Citations: Showing 1 - 2
Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors.
Authors: Ran Et al.
PLoS One 2015;10:e0128619
Canonical Notch signalling is inactive in urothelial carcinoma.
Authors: Greife Et al.
BMC Cancer 2014;14:628
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