Compound W

Catalog # Availability Size / Price Qty
2654/50
Compound W | CAS No. 173550-33-9 | Secretase Inhibitors
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Description: γ-secretase inhibitor
Alternative Names: CW

Chemical Name: 3,5-Bis(4-nitrophenoxy)benzoic acid

Purity: ≥99%

Product Details
Citations (2)
Reviews

Biological Activity

Inhibitor of γ-secretase; causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).

Technical Data

M.Wt:
396.31
Formula:
C19H12N2O8
Solubility:
Soluble to 50 mM in 1.1eq. NaOH and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
173550-33-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Secretion of the notch-1 Aβ-like peptide during notch signaling.
    Okochi et al.
    J.Biol.Chem., 2006;281:7890

Product Datasheets

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Citations for Compound W

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2 Citations: Showing 1 - 2

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