CRHR2/CRF2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-30958

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free
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Product Specifications

Immunogen

Synthetic peptide derived from the N-terminal region of the CRHR2/CRF2 protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for CRHR2/CRF2 Antibody - BSA Free

CRHR2/CRF2 Antibody

Immunohistochemistry: CRHR2/CRF2 Antibody [NBP3-30958] -

Immunohistochemistry: CRHR2/CRF2 Antibody [NBP3-30958] - Staining of normal human colorectal tissue with CRFR1 antibody (Cat. No. NBP3-30958) at 2 ug/ml.

Applications for CRHR2/CRF2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

: 2-10 ug/ml

Western Blot

: 1:400
Application Notes
.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Phosphate buffered saline

Format

BSA Free

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CRHR2

Official Gene Symbol: CRHR2 Gen Bank Accession Number: NP_001874 Gene ID: 1395 (Human) Gene Map Locus: 7p15.1 (Human) CRHR2 is a novel member of Secretin-family-GPCR proteins that functions as a functional receptor for CRF. It is expressed as 3 isoforms; alpha, beta and gamma. These isoforms primarily differ in their N-terminal sequence and tissue distribution. Apart from CRF, other ligands of CRHR2 include UcnI, UcnII and UcnIII. CRHR2 is involved in stress responses, cardiovascular function and gastric motility. Studies on CRHR2 deficient mice suggested a central anxiolytic effect of CRHR2. Northern Blot analysis detects CRHR2 expression in brain, hypothalamus, heart, GI, lung, skeletal muscle and vasculature.

Long Name

Corticotropin Releasing Hormone Receptor 2

Alternate Names

CRF-RB, CRF2, HM-CRF

Gene Symbol

CRHR2

Additional CRHR2 Products

Product Documents for CRHR2/CRF2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for CRHR2/CRF2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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