Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all CTRP2/C1qTNF2 Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the center of human CTRP2. The immunogen is located within amino acids 140 - 190 of CTRP2. Amino Acid Squence: VTKSYPRERLPIKFDK

Specificity

These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit CTRP2 Antibody - BSA Free (NBP1-76627) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CTRP2 Antibody - BSA Free

Western Blot: CTRP2 AntibodyBSA Free [NBP1-76627]

Western Blot: CTRP2 AntibodyBSA Free [NBP1-76627]

Western Blot: CTRP2 Antibody [NBP1-76627] - 3T3 (Balb) cell lysate with CTRP2 (IN) antibody at (A) 1, (B) 2, and (C) 4 ug/ml.
CTRP2 Antibody - BSA Free

Immunohistochemistry: CTRP2 Antibody - BSA Free [NBP1-76627] -

Immunohistochemistry: CTRP2 Antibody - BSA Free [NBP1-76627] - Immunohistochemical staining of human brain tissue using CTRP2 antibody at 10 ug/mL.

Applications for CTRP2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

10 ug/ml

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

1-4 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CTRP2/C1qTNF2

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation.

Long Name

C1q And Tumor Necrosis Factor Related Protein 2

Alternate Names

C1QTNF2, zacrp2

Gene Symbol

C1QTNF2

UniProt

NP_114114 (Human)

Additional CTRP2/C1qTNF2 Products

Product Documents for CTRP2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for CTRP2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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