Cultrex Mouse Collagen IV

Newer Version Available: 3410-010-02

Discontinued Product

3410-010-01 has been discontinued and is replaced by 3410-010-02.

Product Details
Citations (8)

Cultrex Mouse Collagen IV Summary

Endotoxin Level
<20.0 EU per 1 μg of the protein by the LAL method.
Functional Assay: Tested for ability to promote attachment and spreading of rat PC-12 pheochromocytoma cells.


Murine Engelbreth-Holm-Swarm (EHS) tumor.

Product Datasheets


Formulation 0.5 mg/ml.

Purity: > 90% by SDS-PAGE gel.
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Store at -80°C in a manual defrost freezer if using the product within 3 months. Avoid repeated freeze-thaw cycles. For optimal stability, store in liquid nitrogen.

Storage Buffer: 50 mM Hydrochloric Acid, 1 mM TCEP - HCl.

Sterility Testing:
• No bacterial or fungal growth detected after incubation at 37°C for 14 days following USP XXIV Chapter 71 sterility test.
• No mycoplasma contamination detected by PCR.
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Background: Collagen IV

Collagen IV is a primary collagen found in the basement membranes, which underlie epithelial and endothelial cells and surround muscle, fat, and nerve cells. Collagen IV can be used for coating of tissue culture surfaces to promote cell attachment and proliferation and to study its effects on cell behavior.

Alternate Names
Collagen IV

Citations for Cultrex Mouse Collagen IV

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

8 Citations: Showing 1 - 8
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  1. Proplatelet formation is selectively inhibited by collagen type I via Syk-independent GPVI signaling
    J Cell Sci, 2016;0(0):.
  2. Activation of brain endothelial cells by interleukin-1 is regulated by the extracellular matrix after acute brain injury.
    Authors: Summers L, Kangwantas K, Rodriguez-Grande B, Denes A, Penny J, Kielty C, Pinteaux E
    Mol Cell Neurosci, 2013;57(0):93-103.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  3. The impact of extracellular matrix coatings on the performance of human renal cells applied in bioartificial kidneys.
    Authors: Zhang H, Tasnim F, Ying JY, Zink D
    Biomaterials, 2009;30(15):2899-911.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Generation of thymic epithelial cell progenitors by mouse embryonic stem cells.
    Authors: Lai L, Jin J,
    Stem Cells, 2009;27(12):3012-20.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis.
    Authors: Sur I, Rozell B, Jaks V, Bergstrom A, Toftgard R
    J. Cell. Sci., 2006;119(0):3593-601.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  6. Optical control of trimeric P2X receptors and acid-sensing ion channels.
    Authors: Browne L, Nunes J, Sim J, Chudasama V, Bragg L, Caddick S, North R
    Proc Natl Acad Sci U S A, 0;111(1):521-6.
  7. Acidity generated by the tumor microenvironment drives local invasion.
    Authors: Estrella V, Chen T, Lloyd M, Wojtkowiak J, Cornnell H, Ibrahim-Hashim A, Bailey K, Balagurunathan Y, Rothberg J, Sloane B, Johnson J, Gatenby R, Gillies R
    Cancer Res, 0;73(5):1524-35.
  8. Overabundance of putative cancer stem cells in human skin keratinocyte cells malignantly transformed by arsenic.
    Authors: Sun Y, Tokar E, Waalkes M
    Toxicol Sci, 0;125(1):20-9.


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