Curcumin

Catalog # Availability Size / Price Qty
2841/50
Curcumin | CAS No. 458-37-7 | Apoptosis Inducer Compounds
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Description: Antitumor, anti-inflammatory and antioxidant
Alternative Names: Diferuloylmethane

Chemical Name: (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione

Product Details
Citations (5)
Reviews

Biological Activity

Antitumor, anti-inflammatory and antioxidant agent. Downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, iNOS), TNFα, IL-1, IL-6, PKC, EGFR, NF-κB, IκB kinase and more. Upregulates expression of PPARγ, p53, Nrf2. Also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo.

Technical Data

M.Wt:
368.38
Formula:
C21H20O6
Solubility:
Soluble to 10 mM in DMSO and to 5 mM in ethanol
Storage:
Store at -20°C
CAS No:
458-37-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Antitumour, anti-invasion, and antimetastatic effects of curcumin.
    Kuttan et al.
    Adv.Exp.Med.Biol., 2007;595:173
  2. Neuroprotective effects of curcumin.
    Cole et al.
    Adv.Exp.Med.Biol., 2007;595:197
  3. Molecular targets of curcumin.
    Lin
    Adv.Exp.Med.Biol., 2007;595:227
  4. Cardioprotective effects of curcumin.
    Miriyala et al.
    Adv.Exp.Med.Biol., 2007;595:359
  5. Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets.
    Aggarwal and Sung
    TiPS, 2009;30:85

Product Datasheets

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Reconstitution Calculator

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Citations for Curcumin

The citations listed below are publications that use Tocris products. Selected citations for Curcumin include:

5 Citations: Showing 1 - 5

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