Curcumin

  ( 2 citations )    
Product Datasheet
Catalog Number:2841
Alternate Names:Diferuloylmethane
Chemical Name:(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
Product Details
Citations (2)
Reviews
Biological Activity
Antitumor, anti-inflammatory and antioxidant agent. Downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, iNOS), TNFα, IL-1, IL-6, PKC, EGFR, NF-κB, IκB kinase and more. Upregulates expression of PPARγ, p53, Nrf2. Also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo.
Technical Data
  • M.Wt:
    368.38
  • Formula:
    C21H20O6
  • Solubility:
    Soluble to 10 mM in DMSO and to 5 mM in ethanol
  • Storage:
    Store at -20°C
  • CAS No:
    458-37-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Curcumin include:

2 Citations: Showing 1 - 2
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  1. Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin.
    Authors: Chang Et al.
    Sci Rep  2015;5:10256
  2. Rescue of an in vitro neuron phenotype identified in Niemann-Pick disease, type C1 induced pluripotent stem cell-derived neurons by modulating the WNT pathway and calcium signaling.
    Authors: Efthymiou Et al.
    J Neurosci  2015;4:230

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