Cytokeratin 19 Antibody (A53-B/A2.26 + BA17) [DyLight 405]

Novus Biologicals | Catalog # NBP2-34548V

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Mouse IgG2a Lambda/IgG1 Kappa Clone # A53-B/A2.26 + BA17
View all Cytokeratin 19 Primary Antibodies »

Product Specifications

Immunogen

Human breast cancer MCF-7 cells (A53-B/A2); Human mammary epithelial organoids (BA17)

Localization

Cytoplasmic

Marker

Pancreatic Stem Cell Marker

Specificity

This monoclonal antibody reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Lambda/IgG1 Kappa

Description

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Scientific Data Images for Cytokeratin 19 Antibody (A53-B/A2.26 + BA17) [DyLight 405]

Immunohistochemistry-Frozen: Cytokeratin 19 Antibody (A53-B/A2.26 + BA17) [DyLight 405] [NBP2-34548V] - Human breast cancer tissue stained with CK19 antibody. IHC-Fr image submitted by a verified customer review.

Applications for Cytokeratin 19 Antibody (A53-B/A2.26 + BA17) [DyLight 405]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NBP2-34548V in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Cytokeratin 19

Cytokeratin 19 (also known as Keratin, type I cytoskeletal 19) belongs to the keratin family which consists of fibrous proteins that make up the framework of epithelial cells. Cytokeratin 19 plays a role in the organization of myofibers. This protein is known to have interactions with ZNF638, FANCG, FAM107A, KRT15 and EXOC8. Cytokeratin 19 has been studied in relation to several disorders and diseases including chordoma, adenoma, hamartoma, adenoiditis, carcinoma, and liver disease.

Alternate Names

CK19, EndoC, K19, Krt19

Gene Symbol

KRT19

Additional Cytokeratin 19 Products

Product Documents for Cytokeratin 19 Antibody (A53-B/A2.26 + BA17) [DyLight 405]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Cytokeratin 19 Antibody (A53-B/A2.26 + BA17) [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for Cytokeratin 19 Antibody (A53-B/A2.26 + BA17) [DyLight 405] (1)

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  • Cytokeratin 19 Antibody (A53-B/A2.26 + BA17) [DyLight 405]
    Name: Jan Martinek
    Application: Immunohistochemistry-Frozen
    Sample Tested: Breast cancer tissue
    Species: Human
    Verified Customer | Posted 07/20/2020
    Breast cancer tissue stained for cancer cells with anti CK19 antibody
    Acetone fixation
    Cytokeratin 19 Antibody (A53-B/A2.26 + BA17) [DyLight 405] NBP2-34548V

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Protocols

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FAQs

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