DAP12 Antibody (SR3887) - BSA Free

Novus Biologicals | Catalog # NBP3-27816

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR3887 expressed in HEK293

Format

BSA Free
View all DAP12 Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human DAP12 (Uniprot #: O43914)

Specificity

Detects endogenous levels of total DAP12

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

12 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DAP12 Antibody (SR3887) - BSA Free

Western Blot: DAP12 Antibody (SR3887) [NBP3-27816] -

Western Blot: DAP12 Antibody (SR3887) [NBP3-27816] - Western blot analysis of DAP12 expression in Human PBMC cell lysate.

Applications for DAP12 Antibody (SR3887) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:80

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

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Advanced Features

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DAP12

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.

Long Name

DNAX-activation Protein 12

Alternate Names

KARAP, TYROBP

Gene Symbol

TYROBP

Additional DAP12 Products

Product Documents for DAP12 Antibody (SR3887) - BSA Free

Certificate of Analysis

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Product Specific Notices for DAP12 Antibody (SR3887) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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