Diltiazem hydrochloride

Tocris Bioscience | Catalog # 0685

CaV1.x blocker
Tocris Bioscience

Key Product Details

Description

CaV1.x blocker
View all Cav1.x Channel Blockers »

Product Description

Diltiazem hydrochloride is an antihypertensive and cardioprotective agent; an inhibitor of L-type Ca2+ channels.

Product Specifications for Diltiazem hydrochloride

Molecular Weight

450.98

Formula

C22H26N2O4S.HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(2S-cis)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride

CAS Number

33286-22-5

PubChem ID

62920

InChI Key

HDRXZJPWHTXQRI-BHDTVMLSSA-N

SMILES

[H][C@]2(C3=CC=C(OC)C=C3)[C@@]([H])(OC(C)=O)C(N(CCN(C)C)C1=CC=CC=C1S2)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100
DMSO 45.1 100

Preparing Stock Solutions for Diltiazem hydrochloride

The following data is based on the product molecular weight 450.98.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.22 mL 11.09 mL 22.17 mL
5 mM 0.44 mL 2.22 mL 4.43 mL
10 mM 0.22 mL 1.11 mL 2.22 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 22 publications citing the usage of this product.

Product Documents for Diltiazem hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Diltiazem hydrochloride

For research use only

⚠ WARNING: This product can expose you to chemicals including Diltiazem hydrochloride, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Related Research Areas

Ion Channels and Regulators

Citations for Diltiazem hydrochloride

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