Dopamine D3R/DRD3 Antibody

Novus Biologicals | Catalog # NBP3-12391

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Dot Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit
View all Dopamine D3 R/DRD3 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on Dopamine Receptor D3 protein, peptide was covalently modified. Sequence: CQACHVSPELYRATTWGY

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Dopamine D3R/DRD3 Antibody

Western Blot: Dopamine D3R/DRD3 Antibody [NBP3-12391]

Western Blot: Dopamine D3R/DRD3 Antibody [NBP3-12391]

Western Blot: Dopamine D3R/DRD3 Antibody [NBP3-12391] - 1:750 antibody dilution in DiluOBuffer. Predicted bad size 50 KDa. Observed band size 50 KDa.
Immunocytochemistry/ Immunofluorescence: Dopamine D3R/DRD3 Antibody [NBP3-12391]

Immunocytochemistry/ Immunofluorescence: Dopamine D3R/DRD3 Antibody [NBP3-12391]

Immunocytochemistry/Immunofluorescence: Dopamine D3R/DRD3 Antibody [NBP3-12391] - PC12 cells. Cells were incubated with primary antibody 5 ug/ml overnight at 4c.

Applications for Dopamine D3R/DRD3 Antibody

Application
Recommended Usage

Dot Blot

1:50000

ELISA

1:50000

Immunocytochemistry/ Immunofluorescence

5 ug/ul

Western Blot

1:1000-1:15000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: Dopamine D3 R/DRD3

The DRD3 Dopamine Receptor is expressed in brain regions associated with cognitive, emotional, and endocrine functions. DRD3 mediates the effects of drugs used in the treatment of schizophrenia and Parkinson's disease. DRD3 also binds BP897, a potent inhibitor of drug-craving and cocaine-seeking behaviors. Mutations in DRD3 lead to sodium retention in the kidney, resulting in hypertension and increased locomotor activity in mice. Multiple isoforms of DRD3 are produced by alternative splicing.

Long Name

Dopamine D3 Receptor

Alternate Names

D3DR, Dopamine D3R, DRD3, ETM1, FET1

Gene Symbol

DRD3

Additional Dopamine D3 R/DRD3 Products

Product Documents for Dopamine D3R/DRD3 Antibody

Certificate of Analysis

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Product Specific Notices for Dopamine D3R/DRD3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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