Highly potent estrogen ERβ
receptor agonist with a 70-fold selectivity over ERα
values are 0.85 and 66 nM respectively). Relaxes mesenteric arteries in vitro
. Shown to regulate expression of GluR1, GluR2 and GluR3 in rat hippocampus.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Acute effects of oestrogen receptor subtype-specific agonists on vascular contractility.
Montgomery et al.
Estrogen receptor-β potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues.
Meyers et al.
Estrogen receptor alpha and beta specific agonists regulate expression of synaptic proteins in rat hippocampus.
Waters et al.
Brain Res., 2009;1290:1
Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression.
Harrington et al.
The citations listed below are publications that use Tocris products. Selected citations for DPN include:
Showing Results 1 - 10 of 69