DUSP10 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-46621

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all DUSP10 Primary Antibodies »

Product Specifications

Immunogen

dual specificity phosphatase 10. (Uniprot# Q9Y6W6)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DUSP10 Antibody - BSA Free

DUSP10 Antibody - BSA Free

Immunohistochemistry: DUSP10 Antibody - BSA Free [NBP3-46621] -

Immunohistochemistry: DUSP10 Antibody - BSA Free [NBP3-46621] - Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using (DUSP10 Antibody) at dilution of 1:50
DUSP10 Antibody - BSA Free

Western Blot: DUSP10 Antibody - BSA Free [NBP3-46621] -

Western Blot: DUSP10 Antibody - BSA Free [NBP3-46621] - Mouse heart tissue were subjected to SDS PAGE followed by western blot with (DUSP10 antibody) at dilution of 1:500

Applications for DUSP10 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DUSP10

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene.

Alternate Names

dual specificity phosphatase 10, dual specificity phosphatase MKP-5, EC 3.1.3.16, EC 3.1.3.48, MAP kinase phosphatase 5, Mitogen-activated protein kinase phosphatase 5, MKP-5dual specificity protein phosphatase 10, MKP5serine/threonine specific protein phosphatase

Gene Symbol

DUSP10

Additional DUSP10 Products

Product Documents for DUSP10 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for DUSP10 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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