EGCG

  ( 1 citations )    
Product Datasheet
Catalog Number:4524
Alternate Names:Epigallocatechin gallate
Chemical Name:3,4,5-Trihydroxybenzoic acid (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester
Product Details
Citations (1)
Reviews
Biological Activity
β-secretase (BACE1) inhibitor (IC50 = 1.6 μM); inhibits amyloid assembly. Inhibits the formation of amyloid fibrils by proteins such as Aβ, α-synuclein and huntingtin. Reduces Aβ42-induced cell death in three different cell types. Also inhibits glutamate dehydrogenase. Inhibits cell growth and selectively induces apoptosis in A431 and human pancreatic cancer cells. Also a DNMT1 inhibitor.
Technical Data
  • M.Wt:
    458.37
  • Formula:
    C22H18O11
  • Solubility:
    Soluble to 10 mM in water and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    989-51-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for EGCG include:

1 Citations: Showing 1 - 1

  1. Synergistic effect of curcumin on epigallocatechin gallate-induced anticancer action in PC3 prostate cancer cells.
    Authors: Eom Et al.
    Allergy Asthma Immunol Res  2015;48:461

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