Fetal Bovine Serum - Premium

Atlanta Biologicals serum products are now sold under the R&D Systems brand
Want to experience the quality our FBS brings to cell culture? Try a Sample!

Please Note: An additional $10/bottle handling fee will be applied for 500 mL bottles
Catalog # Availability Size / Price Qty
Best Seller
Fetal Bovine Serum - Premium
3 Images
Product Details
Reviews (8)

Fetal Bovine Serum - Premium Summary

Product Datasheets

You must select a language.


Preparation and Storage

On Dry Ice
Stability & Storage
-5 to -20 °C


  1. What is the difference between Fetal Bovine Serum (FBS) and Fetal Calf Serum (FCS)?

    • There is no difference. These are different names for the same product. Serum derived from blood of bovine fetuses is referred to as Fetal Bovine Serum or Fetal Calf Serum.

  2. Should I use heat inactivated fetal bovine serum?

    • Heat inactivation, in general, decreases the growth promoting properties of the serum and causes increased formation of crystalline or flocculent precipitates (salts, proteins, lipids, fibrin, etc.) in the Fetal Bovine Serum (FBS) as well as in other serum products.  In fact, for many cell culture applications, heat inactivation may be unnecessary.  Warming the serum-containing medium to 37˚C prior to use, as is the practice in many cell culture laboratories, is often sufficient to inactivate heat-labile complement factors.  Heat inactivated FBS is frequently used in immunological applications.

      Since every cell type has different growth requirements, the choice of whether to heat inactivate your serum or not must be made by the researcher. If you have concerns about whether to use heat inactivated serum with your cell line or not, perform a side-by-side comparison of cell growth with heat inactivated versus non-heat inactivated serum.

      For your convenience, R&D Systems offers all serum with or without heat-inactivation.

  3. Why is there lot-to-lot variability in serum?

    • Fetal Bovine Serum and other serum products contain a complex mixture of biological components, a majority of which have not yet been fully defined. The composition of these serum components naturally varies from lot-to-lot.

      The best serum lot for you is the one that works for your cells in your specific application. R&D Systems serum manufacturing has a 40 year history of experience, which provides some of the most consistent serum on the market. We can help you select the serum lot that is ideal for your application by offering a variety of programs such as lot matching, free samples for lot prequalification, extended lot reserves, and free on-site serum storage, geared towards minimizing the impact of serum variability for our customers.

View all FAQs

Reviews for Fetal Bovine Serum - Premium

Average Rating: 4.9 (Based on 8 Reviews)

5 Star
4 Star
3 Star
2 Star
1 Star

Have you used Fetal Bovine Serum - Premium?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:

Fetal Bovine Serum - Premium
By Anonymous on 09/07/2023

We employed this serum for fibroblast culturing, and the fibroblasts proliferated while preserving their distinctive differentiation characteristics.

Fetal Bovine Serum - Premium
By Madhu Golla on 11/20/2020

We are currently using this FBS and it is working well and continue to use this in future.
Image Columns
HiTrap Protein G HP, 1 ml

Fetal Bovine Serum - Premium
By Anonymous on 10/19/2020

I used FBS for cell culture.
Image Caption: Zinc Finger expression in PC3 (ATCC-CRL 1435) cell line.

Fetal Bovine Serum - Premium
By Salwa Hafez on 10/18/2019

Works great.

Fetal Bovine Serum - Premium
By Steven Christiansen on 09/12/2019

After doing a thorough Lot test, our lab is confident in the FBS that we ordered from RnD Systems. The attached image is an overlay of Dapi, Phalloidin, and aSMA. Their customer service was also spectacular as we were figuring out exactly what we needed.

Fetal Bovine Serum - Premium
By Anonymous on 05/21/2019

Works perfect with primary fibroblasts and MSCs.

Fetal Bovine Serum - Premium
By John Wise on 05/09/2019

Used to grow alligator lung fibroblasts. Cells grew well. Picture is not the best as our regular camera is down but its the best I could do.

Fetal Bovine Serum - Premium
By Anonymous on 04/05/2019

HCT cells grown in DMEM with 10% serum.