Flt-3 Ligand, also known as FLT3L, is a cytokine that promotes the differentiation or expansion of multiple hematopoietic cell lineages including monocytes, immature dendritic cells, and early B cell lineage cells. It synergizes with other cytokines to promote the myeloid differentiation and mobilization of hematopoietic stem cells, to induce NK cell development, and to induce terminal B cell maturation. Flt-3 Ligand/FLT3L is expressed as a dimer by T cells and bone marrow and thymic fibroblasts. Both transmembrane and soluble forms of Flt-3 Ligand/FLT3L signal through the tyrosine kinase receptor Flt-3/Flk-2.
Flt-3 Ligand/FLT3L Antibody (D13) - BSA Free
Novus Biologicals | Catalog # NBP3-41075
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Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2a Kappa Clone # D13
Format
BSA Free
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Product Specifications
Immunogen
Immunized with recombinant Human Flt-3 Ligand/FLT3L (Uniprot#: P49771; Met83-Pro182 (Uniprot#: P49771)
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2a Kappa
Scientific Data Images for Flt-3 Ligand/FLT3L Antibody (D13) - BSA Free
Western Blot: Flt-3 Ligand/FLT3L Antibody (D13) [NBP3-41075] -
Western Blot: Flt-3 Ligand/FLT3L Antibody (D13) [NBP3-41075] - Sample: Jurkat cell lysate Primary Ab: 3ug/ml NBP3-41075; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Western Blot: Flt-3 Ligand/FLT3L Antibody (D13) [NBP3-41075] -
Western Blot: Flt-3 Ligand/FLT3L Antibody (D13) [NBP3-41075] - Sample: Lane1: Hela cell lysate; Lane2: MCF7 cell lysate Primary Ab: 2ug/ml NBP3-41075; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal AntibodyApplications for Flt-3 Ligand/FLT3L Antibody (D13) - BSA Free
Application
Recommended Usage
Western Blot
0.5-2ug/mL
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
0.01M PBS, pH7.4, 50% glycerol
Format
BSA Free
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Flt-3 Ligand/FLT3L
Long Name
fms-like Tyrosine Kinase 3 Ligand
Alternate Names
FLG3L, Flt3L, FLT3LG
Gene Symbol
FLT3LG
Additional Flt-3 Ligand/FLT3L Products
Product Documents for Flt-3 Ligand/FLT3L Antibody (D13) - BSA Free
Certificate of Analysis
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Product Specific Notices for Flt-3 Ligand/FLT3L Antibody (D13) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
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