Flurizan
Chemical Name: (R)-2-Fluoro-α-methyl[1,1'-biphenyl]-4-acetic acid
Purity: ≥99%
Biological Activity
Nonsteroidal anti-inflammatory drug (NSAID) that inhibits γ-secretase activity. Selectively lowers Aβ42 levels in human neuroglioma cells; displays no effect on Aβ40 levels at a concentration of 100 μM.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice.
Kukar et al.
BMC Neurosci., 2007;8:54 -
NSAIDs and enantiomers of flurbip. target γ-secretase and lower Aβ42 in vivo.
Eriksen et al.
J.Clin.Invest., 2003;112:440
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Flurizan
There are currently no reviews for this product. Be the first to review Flurizan and earn rewards!
Have you used Flurizan?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
