GAB1 Antibody (1A7) - BSA Free

Novus Biologicals | Catalog # NBP2-37742

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Flow Cytometry, CyTOF-ready

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 1A7

Format

BSA Free
View all GAB1 Primary Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human GAB1 expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

76.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for GAB1 Antibody (1A7) - BSA Free

Western Blot: GAB1 Antibody (1A7)BSA Free [NBP2-37742]

Western Blot: GAB1 Antibody (1A7)BSA Free [NBP2-37742]

Western Blot: GAB1 Antibody (1A7) [NBP2-37742] - Analysis using GAB1 mouse mAb against HEK293 (1) cell lysate.
Immunohistochemistry-Paraffin: GAB1 Antibody (1A7) - BSA Free [NBP2-37742]

Immunohistochemistry-Paraffin: GAB1 Antibody (1A7) - BSA Free [NBP2-37742]

Immunohistochemistry-Paraffin: GAB1 Antibody (1A7) [NBP2-37742] - Analysis of bladder cancer tissues using GAB1 mouse mAb with DAB staining.
Flow Cytometry: GAB1 Antibody (1A7) - BSA Free [NBP2-37742]

Flow Cytometry: GAB1 Antibody (1A7) - BSA Free [NBP2-37742]

Flow Cytometry: GAB1 Antibody (1A7) [NBP2-37742] - Analysis of Jurkat cells using GAB1 mouse mAb (green) and negative control (red).
Western Blot: GAB1 Antibody (1A7)BSA Free [NBP2-37742]

Western Blot: GAB1 Antibody (1A7)BSA Free [NBP2-37742]

Western Blot: GAB1 Antibody (1A7) [NBP2-37742] - Analysis using GAB1 mAb against human GAB1 (AA: 661-724) recombinant protein. (Expected MW is 32.4 kDa)
Immunohistochemistry-Paraffin: GAB1 Antibody (1A7) - BSA Free [NBP2-37742]

Immunohistochemistry-Paraffin: GAB1 Antibody (1A7) - BSA Free [NBP2-37742]

Immunohistochemistry-Paraffin: GAB1 Antibody (1A7) [NBP2-37742] - Analysis of kidney tissues using GAB1 mouse mAb with DAB staining.
ELISA: GAB1 Antibody (1A7) - BSA Free [NBP2-37742]

ELISA: GAB1 Antibody (1A7) - BSA Free [NBP2-37742]

ELISA: GAB1 Antibody (1A7) [NBP2-37742] - Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng);

Applications for GAB1 Antibody (1A7) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200 - 1:400

Immunohistochemistry

1:200 - 1:1000

Immunohistochemistry-Paraffin

1:200 - 1:1000

Western Blot

1:500 - 1:2000
Application Notes
This antibody is Cytof ready.

Flow Cytometry Panel Builder

Bio-Techne Knows Flow Cytometry

Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
  • Spillover Popups - Visualize the spectra of individual fluorochromes
  • Antigen Density Selector - Match fluorochrome brightness with antigen density
Build Your Panel Now
Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GAB1

Growth factor triggering of protein tyrosine kinase receptors induces signals that cascade to the nucleus, activating mitogenic as well as other responses. Critical components of this process include adapter protein such as Shc, IRS-1 and Gab 1 (GRB-associated binder-1) that lack detectable catalytic activity. These are immediate substrates of receptor tyrosine kinase activity and serve to link activated receptors to downstream signaling components. Whereas Shc has been implicated in signaling by diverse receptor families, IRS-1 serves primarily as the major insulin receptor substrate. Shc and Gab 1 also participate in insulin signaling by linking the insulin receptor to Ras by forming complexes with GRB2 (another adapter protein) and Sos independently of IRS-1. Gab 1 is also thought to be involved in the EGF receptor signaling pathway.

Long Name

GRB2-associated Binding Protein 1

Alternate Names

GRB2-associated binder 1, GRB2-associated binding protein 1, GRB2-associated-binding protein 1, Growth factor receptor bound protein 2-associated protein 1

Gene Symbol

GAB1

Additional GAB1 Products

Product Documents for GAB1 Antibody (1A7) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for GAB1 Antibody (1A7) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for GAB1 Antibody (1A7) - BSA Free

There are currently no reviews for this product. Be the first to review GAB1 Antibody (1A7) - BSA Free and earn rewards!

Have you used GAB1 Antibody (1A7) - BSA Free?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies