GABA-AR alpha 4 Antibody

Name: GABA-AR alpha 4 Antibody
Brand: Novus Biologicals
SKU: NBP1-18844
Price: 399 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-18844

Submit a review

Citations (1)

Product Documents

100% Guarantee

Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

View all GABA-A R alpha 4 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EKAKRKTSKPPQE corresponding to internal region according to NP_000800.2.

Epitope

internal region

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for GABA-AR alpha 4 Antibody

Western Blot: GABA-AR alpha 4 Antibody [NBP1-18844]

Western Blot: GABA-A R alpha 4 Antibody [NBP1-18844] - Analysis of GABA A Receptor alpha 4 in Human Frontal Cortex lysate (35ug protein in RIPA buffer) using this antibody at 0.1 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Immunohistochemistry-Paraffin: GABA-AR alpha 4 Antibody [NBP1-18844]

Immunohistochemistry-Paraffin: GABA-A R alpha 4 Antibody [NBP1-18844] - (2.5ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for GABA-AR alpha 4 Antibody

Application

Recommended Usage

Immunohistochemistry

2 - 4 ug/ml

Immunohistochemistry-Paraffin

2 - 4 ug/ml

Peptide ELISA

Detection limit 1:16000

Western Blot

0.1 - 0.3 ug/ml

Application Notes

WB: Approx. 70 kDa band observed in human brain (cerebellum and frontal cortex) lysates (calculated MW of 61.6 kDa band according to NP_000800.2). IHC-P: Human cortex shows patchy staining near or at the neuronal cell membrane.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GABA-A R alpha 4

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq]

Long Name

gamma-Aminobutyric Acid Type A Receptor, alpha-4 Polypeptide

Alternate Names

GABAAR alpha 4, GABAARa4, GABRA4

Entrez Gene IDs

2557 (Human)

Gene Symbol

GABRA4

UniProt

NP_000800.2 (Human)

Additional GABA-A R alpha 4 Products

Product Documents for GABA-AR alpha 4 Antibody

Download Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for GABA-AR alpha 4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

GABA Receptors

Citations for GABA-AR alpha 4 Antibody

Customer Reviews for GABA-AR alpha 4 Antibody

There are currently no reviews for this product. Be the first to review GABA-AR alpha 4 Antibody and earn rewards!

Have you used GABA-AR alpha 4 Antibody?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image