HINT1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-76944

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Rabbit (100%). Backed by our 100% Guarantee.

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all HINT1 Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide near the center of the human HINT1. The immunogen is located within the last 50 amino acids of HINT1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HINT1 Antibody - BSA Free

Western Blot: HINT1 AntibodyBSA Free [NBP1-76944]

Western Blot: HINT1 AntibodyBSA Free [NBP1-76944]

Western Blot: HINT1 Antibody [NBP1-76944] - Jurkat lysate with HINT1 antibody at (A) 1 and (B) 2 ug/mL.
HINT1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: HINT1 Antibody - BSA Free [NBP1-76944] -

Immunocytochemistry/ Immunofluorescence: HINT1 Antibody - BSA Free [NBP1-76944] - Immunocytochemistry of HINT1 in Jurkat cells with HINT1 antibody at 2.5 ug/mL.

Applications for HINT1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2.5 ug/mL

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HINT1

Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.

Alternate Names

Adenosine 5'-monophosphoramidase, EC 3.-, HINT, histidine triad nucleotide binding protein 1, histidine triad nucleotide-binding protein, histidine triad nucleotide-binding protein 1, PKCI1, PKCI-1FLJ30414, PRKCNH1FLJ32340, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1

Gene Symbol

HINT1

UniProt

NP_005331 (Human)

Additional HINT1 Products

Product Documents for HINT1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for HINT1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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