Histone H2AE [p Ser1] Antibody (RM216) [Alexa Fluor™ Plus 488]

Novus Biologicals | Catalog # NBP3-26017AFP488

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human, Vertebrate

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Alexa Fluor Plus 488

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM216
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Product Specifications

Immunogen

An unmodified peptide corresponding to the N-terminus of Histone H2AE

Modification

p Ser1

Specificity

This antibody reacts to Histone H4 or Histone H2AE phosphorylated at Serine 1. No cross reactivity with other phosphorylated Histones.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for Histone H2AE [p Ser1] Antibody (RM216) [Alexa Fluor™ Plus 488]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Histone H2AE

Histone H2AE is 124 amino acids long, weighing approximately 13 kDa, and is part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes and is a core component of the nucleosome. Current studies are being done on several diseases and disorders including riddle syndrome, systemic lupus erythematosus, lupus srythematosus, and immunodeficiency. This protein has also been shown to have interactions with HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H4E in pathways such as the proteasome degradation, nucleosome assembly, cell cycle, and systemic lupus erythematosus pathways.

Alternate Names

H2A histone family, member M, H2A/m, H2AFA, H2AFMHistone H2A/m, HIST1H2AE, histone 1, H2ab, histone cluster 1, H2ab, histone H2A type 1-B/E, Histone H2A.2, Histone H2A/a

Gene Symbol

H2AC8

Additional Histone H2AE Products

Product Documents for Histone H2AE [p Ser1] Antibody (RM216) [Alexa Fluor™ Plus 488]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Histone H2AE [p Ser1] Antibody (RM216) [Alexa Fluor™ Plus 488]



This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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