Human Angiopoietin-2 Quantikine ELISA Kit Summary
Product Summary
Precision
Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 40 | 40 | 40 |
Mean | 237 | 703 | 1301 | 276 | 805 | 1494 |
Standard Deviation | 16.4 | 45.6 | 54.4 | 28.8 | 73 | 111 |
CV% | 6.9 | 6.5 | 4.2 | 10.4 | 9.1 | 7.4 |
Recovery
The recovery of Angiopoietin-2 spiked to levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Media (n=4) | 103 | 98-113 |
EDTA Plasma (n=4) | 95 | 85-104 |
Heparin Plasma (n=4) | 94 | 87-104 |
Serum (n=4) | 100 | 90-107 |
Linearity
Data Examples
Product Datasheets
Preparation and Storage
Background: Angiopoietin-2
Angiopoietins, Ang-1, Ang-2, and Ang-3 (mouse)/Ang-4 (human), are natural agonists or antagonists of the Tie-2 receptor tyrosine kinase and are important modulators of angiogenesis. Two domains characterize the angiopoietin family of proteins: an N-terminal coiled-coil domain that mediates homo-oligomerization, and a C-terminal fibrinogen-like domain that binds Tie-2.
Assay Procedure
Refer to the product- Prepare all reagents, standard dilutions, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 100 µL of Assay Diluent to each well.
- Add 50 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours on a horizontal orbital microplate shaker.
- Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.
- Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours on the shaker.
- Aspirate and wash 4 times.
- Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes on the benchtop. PROTECT FROM LIGHT.
- Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.





Citations for Human Angiopoietin-2 Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Adhesion of T cells to endothelial cells facilitates blinatumomab-associated neurologic adverse events
Authors: M Klinger, G Zugmaier, V Nägele, ME Goebeler, C Brandl, M Stelljes, H Lassmann, A von Stacke, RC Bargou, P Kufer
Cancer Res., 2019;0(0):.
Species: Human
Sample Types: Plasma
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Hematoma-derived exosomes of chronic subdural hematoma promote abnormal angiogenesis and inhibit hematoma absorption through miR-144-5p
Authors: C Gao, Z Gong, D Wang, J Huang, Y Qian, M Nie, W Jiang, X Liu, H Luo, J Yuan, T Xiang, S An, W Quan, H Wei, J Zhang, R Jiang
Aging (Albany NY), 2019;11(24):12147-12164.
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Systemic Inflammation Precedes Microalbuminuria in Diabetes
Authors: FG Scurt, J Menne, S Brandt, A Bernhardt, PR Mertens, H Haller, C Chatzikyrk,
Kidney Int Rep, 2019;4(10):1373-1386.
Species: Human
Sample Types: Serum
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Relationship of mottling score, skin microcirculatory perfusion indices and biomarkers of endothelial dysfunction in patients with septic shock: an observational study
Authors: S Kazune, A Caica, K Volceka, O Suba, U Rubins, A Grabovskis
Crit Care, 2019;23(1):311.
Species: Human
Sample Types: Plasma
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Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels
Authors: NAM Dekker, ALI van Leeuwe, WWJ van Strien, J Majolée, R Szulcek, ABA Vonk, PL Hordijk, C Boer, CE van den Br
Crit Care, 2019;23(1):117.
Species: Human
Sample Types: Plasma
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Fibroblast growth factor 23, endothelium biomarkers and acute kidney injury in critically-ill patients
Authors: FM de Oliveir, CB Araújo, DF de Freitas, BFT Arruda, LJM de Macêdo, VB Salles, GC Meneses, AMC Martins, AB Libório
J Transl Med, 2019;17(1):121.
Species: Human
Sample Types: Plasma
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Angiogenic Properties of Menstrual Stem Cells Are Impaired in Women with a History of Preeclampsia
Authors: M Varas-Godo, S Acuña-Gall, S Venegas-Du, C Hill, A Caceres-Ve, O Realini, LJ Monteiro, G Zavala, M Khoury, R Romero, G Rice, SE Illanes
Stem Cells Int, 2019;2019(0):1916542.
Species: Human
Sample Types: Cell Culture Supernates
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Nesfatin-1 and visfatin expression is associated with reduced atherosclerotic disease risk in patients with rheumatoid arthritis
Authors: C Robinson, L Tsang, A Solomon, AJ Woodiwiss, S Gunter, M Mer, HC Hsu, M Gomes, GR Norton, AME Millen, PH Dessein
Peptides, 2018;102(0):31-37.
Species: Human
Sample Types: Plasma
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Different patterns of inflammatory and angiogenic factors are associated with peritoneal small solute transport and peritoneal protein clearance in peritoneal dialysis patients
Authors: Y Shi, H Yan, J Yuan, H Zhang, J Huang, Z Ni, J Qian, W Fang
BMC Nephrol, 2018;19(1):119.
Species: Human
Sample Types: Serum
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Does the Automatic Measurement of Interleukin 6 Allow for Prediction of Complications during the First 48 h of Acute Pancreatitis?
Authors: W Kolber, P Dumnicka, M Maraj, B Ku?nierz-C, P Ceranowicz, M P?dziwiatr, B Maziarz, M Mazur-Lask, M Ku?niewski, M Sporek, J Walocha
Int J Mol Sci, 2018;19(6):.
Species: Human
Sample Types: Serum
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Profiling of selected angiogenesis-related genes in serous ovarian cancer patients
Authors: P Ku?, R Charkiewic, D Klasa-Mazu, T Milczek, B Mroczko, J Nikli?ski, P Lauda?ski
Adv Med Sci, 2017;62(1):116-120.
Species: Human
Sample Types: Cell Lysates
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Shear stress-regulated miR-27b controls pericyte recruitment by repressing SEMA6A and SEMA6D
Authors: S Demolli, A Doddaballa, K Devraj, K Stark, Y Manavski, A Eckart, CM Zehendner, T Lucas, T Korff, M Hecker, S Massberg, S Liebner, D Kaluza, RA Boon, S Dimmeler
Cardiovasc. Res., 2017;113(6):681-691.
Species: Human
Sample Types: Cell Lysates
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Tie2 as a novel key factor of microangiopathy in systemic sclerosis
Authors: F Moritz, J Schniering, JHW Distler, RE Gay, S Gay, O Distler, B Maurer
Arthritis Res. Ther., 2017;19(1):105.
Species: Human
Sample Types: Serum
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Myeloperoxidase-derived 2-chlorofatty acids contribute to human sepsis mortality via acute respiratory distress syndrome
Authors: NJ Meyer, JP Reilly, R Feng, JD Christie, SL Hazen, CJ Albert, JD Franke, CL Hartman, J McHowat, DA Ford
JCI Insight, 2017;2(23):.
Species: Human
Sample Types: Cell Culture Supernates
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Angiopoietin-2 and soluble Tie-2 receptor plasma levels in children with obstructive sleep apnea and obesity
Authors: D Gozal, A Khalyfa, Z Qiao, DL Smith, MF Philby, D Koren, L Kheirandis
Obesity (Silver Spring), 2017;0(0):.
Species: Human
Sample Types: Plasma
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The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration
Authors: K Wang, W Liu, Y Song, X Wu, Y Zhang, S Li, Y Gao, J Tu, Y Liu, C Yang
Lab. Invest., 2017;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Serum Concentrations of Angiopoietin-2 and Soluble fms-Like Tyrosine Kinase 1 (sFlt-1) Are Associated with Coagulopathy among Patients with Acute Pancreatitis
Authors: P Dumnicka, B Ku?nierz-C, M Sporek, M Mazur-Lask, K Gil, M Ku?niewski, P Ceranowicz, Z Warzecha, A Dembi?ski, J Bonior, R Dro?d?
Int J Mol Sci, 2017;18(4):.
Species: Human
Sample Types: Serum
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Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling
Sci Rep, 2016;6(0):29029.
Species: Human
Sample Types: Cell Culture Supernates
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Angiopoietin-2, Angiopoietin-1 and subclinical cardiovascular disease in Chronic Kidney Disease
Sci Rep, 2016;6(0):39400.
Species: Human
Sample Types: Serum
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Neovascularization Potential of Blood Outgrowth Endothelial Cells From Patients With Stable Ischemic Heart Failure Is Preserved
Authors: D Dauwe, B Pelacho, A Wibowo, AS Walravens, K Verdonck, H Gillijns, E Caluwe, P Pokreisz, N van Gastel, G Carmeliet, M Depypere, F Maes, N Vanden Dri, W Droogne, J Van Cleemp, J Vanhaecke, F Prosper, C Verfaillie, A Luttun, S Janssens
J Am Heart Assoc, 2016;5(4):.
Species: Human
Sample Types: Cell Culture Supernates
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IL-35 Inhibits Angiogenesis through VEGF/Ang2/Tie2 Pathway in Rheumatoid Arthritis
Authors: Shenyi Jiang
Cell. Physiol. Biochem, 2016;40(5):1105-1116.
Species: Human
Sample Types: Cell Culture Supernates
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TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1
Sci Adv, 2016;2(4):e1501290.
Species: Human
Sample Types: Cell Lysates
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Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass.
Authors: Jongman R, van Klarenbosch J, Molema G, Zijlstra J, de Vries A, van Meurs M
PLoS ONE, 2015;10(8):e0136205.
Species: Human
Sample Types: Plasma
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Combining bevacizumab and chemoradiation in rectal cancer. Translational results of the AXEBeam trial.
Authors: Verstraete M, Debucquoy A, Dekervel J, Van Pelt J, Verslype C, Devos E, Chiritescu G, Dumon K, D'Hoore A, Gevaert O, Sagaert X, Van Cutsem E, Haustermans K
Br J Cancer, 2015;112(8):1314-25.
Species: Human
Sample Types: Whole Blood
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Kidney function, endothelial activation and atherosclerosis in black and white Africans with rheumatoid arthritis.
Authors: Dessein, Patrick, Hsu, Hon-Chun, Tsang, Linda, Millen, Aletta M, Woodiwiss, Angela J, Norton, Gavin R, Solomon, Ahmed, Gonzalez-Gay, Miguel A
PLoS ONE, 2015;10(3):e0121693.
Species: Human
Sample Types: Plasma
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Mechanism of angiopoietin-1 upregulation in Kaposi's sarcoma-associated herpesvirus-infected PEL cell lines.
Authors: Zheng X, Ohsaki E, Ueda K
J Virol, 2015;89(9):4786-97.
Species: Human
Sample Types: Cell Culture Supernates
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A randomized phase II study of capecitabine-based chemoradiation with or without bevacizumab in resectable locally advanced rectal cancer: clinical and biological features.
Authors: Salazar R, Capdevila J, Laquente B, Manzano J, Pericay C, Villacampa M, Lopez C, Losa F, Safont M, Gomez A, Alonso V, Escudero P, Gallego J, Sastre J, Gravalos C, Biondo S, Palacios A, Aranda E
BMC Cancer, 2015;15(0):60.
Species: Human
Sample Types: Plasma
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Association of angiopoietin-2 with renal outcome in chronic kidney disease.
Authors: Tsai, Yi-Chun, Chiu, Yi-Wen, Tsai, Jer-Chia, Kuo, Hung-Tie, Lee, Su-Chu, Hung, Chi-Chih, Lin, Ming-Yen, Hwang, Shang-Jy, Kuo, Mei-Chua, Chen, Hung-Chu
PLoS ONE, 2014;9(10):e108862.
Species: Human
Sample Types: Plasma
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Angiopoietin-2 and angiopoietin-2/angiopoietin-1 ratio as indicators of potential severity of Plasmodium vivax malaria in patients with thrombocytopenia.
Authors: Gomes L, Alves-Junior E, Rodrigues-Jesus C, Nery A, Gasquez-Martin T, Fontes C
PLoS ONE, 2014;9(10):e109246.
Species: Human
Sample Types: Serum
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Angiopoietin-2 and biliary diseases: elevated serum, but not bile levels are associated with cholangiocarcinoma.
Authors: Voigtlander T, David S, Thamm K, Schlue J, Metzger J, Manns M, Lankisch T
PLoS ONE, 2014;9(5):e97046.
Species: Human
Sample Types: Bile
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Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer.
Authors: Sallinen H, Heikura T, Koponen J, Kosma V, Heinonen S, Yla-Herttuala S, Anttila M
BMC Cancer, 2014;14(0):696.
Species: Human
Sample Types: Serum
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Mobilization of circulating endothelial progenitor cells correlates with the clinical course of hantavirus disease.
Authors: Krautkramer E, Grouls S, Hettwer D, Rafat N, Tonshoff B, Zeier M
J Virol, 2014;88(1):483-9.
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Clinical outcome, proteome kinetics and angiogenic factors in serum after thermoablation of colorectal liver metastases.
Authors: Wertenbroek, Marieke, Schepers, Marianne, Kamminga-Rasker, Hannetta, Bottema, Jan T, Muller Kobold, Anneke C, Roelofsen, Han, de Jong, Koert P
BMC Cancer, 2013;13(1):266.
Species: Human
Sample Types: Serum
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Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer.
Authors: Schauer D, Starlinger P, Reiter C, Jahn N, Zajc P, Buchberger E, Bachleitner-Hofmann T, Bergmann M, Stift A, Gruenberger T, Brostjan C
PLoS ONE, 2012;7(9):e44450.
Species: Human
Sample Types: Plasma
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Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma.
Authors: Llovet JM, Pena CE, Lathia CD, Shan M, Meinhardt G, Bruix J, Pallota MG, Zarba JJ, Boyer M, Riordan S, Strickland A, Tebbutt N, Thomson B, Borbath I, De Greve J, Van Laethem J-, Van Steenbergen W, Van Vlierberghe H, Barrios C, Cosme de Oliveira A, Kotzev I, Takov D, Tchernev K, Burak K, Ma M, Metrakos P, Olweny C, Sherman M, Gamargo Garate C, Martinez-Castillo J, Beaugrand M, Bennouna J, Blanc J-, Bronowicki J-, Degos F, Dominguez S, Grange J-, Hillon P, Raoul J-, Seitz J-, Blum H, Buggisch P, Caspary W, Dollinger M, Gerken G, Goke B, Gregor M, Greten T, Haussinger D, Hilgard P, Scherübl J, Scheulen M, Schmid R, Spengler U, Wiest R, Zeuzem S, Arvanitakis C, Germanidis G, Katsos I, Figer A, Stemmer S, Amadori D, Bolondi L, Cognetti F, Craxi A, Farinati F, Gridelli C, Martoni A, Mazzaferro V, Porta C, Ricci S, Sangiovanni A, Santoro A, Trevisani F, Cisnero Garza LE, Gane E, O'Donnell A, Leon J, Lozano A, Jassem J, Rydzewska G, Szawlowski A, Tomczak P, Badulescu F, Miron L, Kubyshkin V, Bruix J, Forner A, Bustamante Schneider J, Diago M, Montero Alvarez JL, Pascual S, RuÃÂz del Arbol L, Sangro B, Solá R, Tabernero J, Muellhaupt B, Roth A, Jeffry Evans TR, Falk S, Meyer T, Reeves H, Ross P, Befeler A, Boyer T, Britten C, Byrne T, Garcia-Tsao G, Gold P, Goldenberg A, Heuman D, Kennedy P, Koch A, Llovet JM, Marrero J, Schilsky M, Schwartz J, Schwartz M
Clin. Cancer Res., 2012;18(8):2290-300.
Species: Human
Sample Types: Plasma
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Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax.
Proc Natl Acad Sci U S A, 2012;109(25):10024-9.
Species: Primate - Papio cynocephalus (Yellow Baboon)
Sample Types: Serum
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Circulating angiopoietin-2 and soluble Tie-2 in type 2 diabetes mellitus: a cross-sectional study.
Authors: Rasul S, Reiter MH, Ilhan A, Lampichler K, Wagner L, Kautzky-Willer A
Cardiovasc Diabetol, 2011;10(0):55.
Species: Human
Sample Types: Plasma
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Association of angiopoietin-2, C-reactive protein and markers of obesity and insulin resistance with survival outcome in colorectal cancer.
Authors: Volkova E, Willis JA, Wells JE, Robinson BA, Dachs GU, Currie MJ
Br. J. Cancer, 2011;104(1):51-9.
Species: Human
Sample Types: Serum
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Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair.
Authors: Li TS, Cheng K, Malliaras K, Matsushita N, Sun B, Marban L, Zhang Y, Marban E
Cardiovasc. Res., 2011;89(1):157-65.
Species: Human
Sample Types: Cell Culture Supernates
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Effect of prostaglandin F2 alpha on local luteotropic and angiogenic factors during induced functional luteolysis in the bovine corpus luteum.
Authors: Berisha B, Meyer HH, Schams D
Biol. Reprod., 2010;82(5):940-7.
Species: Bovine
Sample Types: Tissue Homogenates
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Signs of reduced angiogenic activity after surgical removal of deeply infiltrating endometriosis.
Authors: Bourlev V, Iljasova N, Adamyan L, Larsson A, Olovsson M
Fertil. Steril., 2010;94(1):52-7.
Species: Human
Sample Types: Serum
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Defective angiogenesis in hypoplastic human fetal lungs correlates with nitric oxide synthase deficiency that occurs despite enhanced angiopoietin-2 and VEGF.
Authors: Boucherat O, Franco-Montoya ML, Delacourt C, Martinovic J, Masse V, Elie C, Thebaud B, Benachi A, Bourbon JR
Am. J. Physiol. Lung Cell Mol. Physiol., 2010;298(6):L849-56.
Species: Human
Sample Types: Tissue Homogenates
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Changes in circulating levels and ratios of angiopoietins during pregnancy but not during the menstrual cycle and controlled ovarian stimulation.
Authors: Hurliman AK, Speroff L, Stouffer RL, Patton PE, Lee A, Molskness TA
Fertil. Steril., 2010;93(5):1493-9.
Species: Human
Sample Types: Serum
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Angiopoietin-2 plasma dosage predicts time to first treatment and overall survival in chronic lymphocytic leukemia.
Authors: Maffei R, Martinelli S, Santachiara R
Blood, 2010;116(4):584-92.
Species: Human
Sample Types: Plasma
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Colorectal resection is associated with persistent proangiogenic plasma protein changes: postoperative plasma stimulates in vitro endothelial cell growth, migration, and invasion.
Authors: Shantha Kumara HM, Feingold D, Kalady M, Dujovny N, Senagore A, Hyman N, Cekic V, Whelan RL
Ann. Surg., 2009;249(6):973-7.
Species: Human
Sample Types: Plasma
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Increased plasma EPO and MIP-1 alpha are associated with recruitment of vascular progenitors but not CD34(+) cells in autologous peripheral blood stem cell grafts.
Authors: Labonte L, Li Y, Yang L, Gillingham A, Halpenny M, Giulivi A, Sills T, Evans K, Zanke B, Allan DS
Exp. Hematol., 2009;37(6):673-8.
Species: Human
Sample Types: Plasma
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Changes in vascular endothelial growth factor, angiopoietins, and Tie-2 levels with G-CSF stimulation in healthy donors.
Authors: Serefhanoglu S, Goker H, Buyukasik Y, Turgut M, Sayinalp N, Haznedaroglu IC, Aksu S, Akman U, Ozcebe OI
Ann. Hematol., 2009;88(7):667-71.
Species: Human
Sample Types: Plasma
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Angiopoietin-2 levels are associated with disease progression in metastatic malignant melanoma.
Authors: Helfrich I, Edler L, Sucker A, Thomas M, Christian S, Schadendorf D, Augustin HG
Clin. Cancer Res., 2009;15(4):1384-92.
Species: Human
Sample Types: Serum
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Structural stability of neoangiogenic intramyocardial microvessels supports functional recovery in chronic ischemic myocardium.
Authors: Shim WS, Lim SY, Li SQ, Gu Y, Ong HC, Song IC, Chuah SC, Wong P
J. Mol. Cell. Cardiol., 2008;45(1):70-80.
Species: Porcine
Sample Types: Tissue Homogenates
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Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?
Authors: Ganter MT, Cohen MJ, Brohi K, Chesebro BB, Staudenmayer KL, Rahn P, Christiaans SC, Bir ND, Pittet JF
Ann. Surg., 2008;247(2):320-6.
Species: Human
Sample Types: Plasma
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Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease.
Authors: Findley CM, Mitchell RG, Duscha BD, Annex BH, Kontos CD
J. Am. Coll. Cardiol., 2008;52(5):387-93.
Species: Human
Sample Types: Plasma
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Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.
Authors: Sorrentino A, Ferracin M, Castelli G, Biffoni M, Tomaselli G, Baiocchi M, Fatica A, Negrini M, Peschle C, Valtieri M
Exp. Hematol., 2008;36(8):1035-46.
Species: Human
Sample Types: Cell Culture Supernates
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Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria.
Authors: Yeo TW, Lampah DA, Gitawati R, Tjitra E, Kenangalem E, Piera K, Price RN, Duffull SB, Celermajer DS, Anstey NM
Proc. Natl. Acad. Sci. U.S.A., 2008;105(44):17097-102.
Species: Human
Sample Types: Plasma
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Roles of angiopoietin-1 and angiopoietin-2 on airway microvascular permeability in asthmatic patients.
Authors: Kanazawa H, Nomura S, Asai K
Chest, 2007;131(4):1035-41.
Species: Human
Sample Types: Sputum
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Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients.
Authors: Caine GJ, Ryan P, Lip GY, Blann AD
Cancer Lett., 2007;251(2):296-301.
Species: Human
Sample Types: Plasma
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Serum concentrations of angiogenic cytokines in Waldenstrom macroglobulinaemia: the ration of angiopoietin-1 to angiopoietin-2 and angiogenin correlate with disease severity.
Authors: Anagnostopoulos A, Eleftherakis-Papaiakovou V, Kastritis E, Tsionos K, Bamias A, Meletis J, Dimopoulos MA, Terpos E
Br. J. Haematol., 2007;137(6):560-8.
Species: Human
Sample Types: Serum
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Serum angiopoietin-2 as a clinical marker for lung cancer.
Authors: Park JH, Park KJ, Kim YS, Sheen SS, Lee KS, Lee HN, Oh YJ, Hwang SC
Chest, 2007;132(1):200-6.
Species: Human
Sample Types: Serum
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Angiopoietin-2 as a contributing factor of exercise-induced bronchoconstriction in asthmatic patients receiving inhaled corticosteroid therapy.
Authors: Kanazawa H, Tochino Y, Asai K
J. Allergy Clin. Immunol., 2007;121(2):390-5.
Species: Human
Sample Types: Sputum
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Relationship of soluble CD40 ligand to vascular endothelial growth factor, angiopoietins, and tissue factor in atrial fibrillation: a link among platelet activation, angiogenesis, and thrombosis?
Authors: Choudhury A, Freestone B, Patel J, Lip GY
Chest, 2007;132(6):1913-9.
Species: Human
Sample Types: Plasma
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Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer.
Authors: Caine GJ, Stonelake PS, Lip GY, Blann AD
Cancer Lett., 2007;248(1):131-6.
Species: Human
Sample Types: Plasma
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Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia.
Authors: Lee CY, Tien HF, Hu CY, Chou WC, Lin LI
Br. J. Cancer, 2007;97(7):877-82.
Species: Human
Sample Types: Plasma
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Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoietin-2 expression in lymphatic endothelial cells.
Authors: Vart RJ, Nikitenko LL, Lagos D, Trotter MW, Cannon M, Bourboulia D, Gratrix F, Takeuchi Y, Boshoff C
Cancer Res., 2007;67(9):4042-51.
Species: Human
Sample Types: Cell Culture Supernates
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Differential levels of soluble angiopoietin-2 and Tie-2 in patients with haematological malignancies.
Authors: Quartarone E, Alonci A, Allegra A, Bellomo G, Calabro L, D'Angelo A, Del Fabro V, Grasso A, Cincotta M, Musolino C
Eur. J. Haematol., 2006;77(6):480-5.
Species: Human
Sample Types: Serum
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Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death.
Authors: Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA
Nat. Med., 2006;12(11):1286-93.
Species: Human
Sample Types: Plasma
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Angiopoietin 1 (Ang-1), angiopoietin 2 (Ang-2) and Tie-2 (a receptor tyrosine kinase) concentrations in peripheral blood of patients with thyroid cancers.
Authors: Niedzwiecki S, Stepien T, Kopec K, Kuzdak K, Komorowski J, Krupinski R, Stepien H
Cytokine, 2006;36(5):291-5.
Species: Human
Sample Types: Serum
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Potential role of soluble angiopoietin-2 and Tie-2 in patients with inflammatory bowel disease.
Authors: Koutroubakis IE, Xidakis C, Karmiris K, Sfiridaki A, Kandidaki E, Kouroumalis EA
Eur. J. Clin. Invest., 2006;36(2):127-32.
Species: Human
Sample Types: Serum
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Circulating levels of total angiopoietin-2 and the soluble Tie-2 receptor in women during ovarian stimulation and early gestation.
Authors: Molskness TA, Stouffer RL, Burry KA, Gorrill MJ, Lee DM, Patton PE
Fertil. Steril., 2006;86(5):1531-3.
Species: Human
Sample Types: Serum
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Differential expression of angiopoietin-1, angiopoietin-2, and Tie receptors in placentas from pregnancies complicated by placenta accreta.
Authors: Tseng JJ, Hsu SL, Ho ES, Hsieh YT, Wen MC, Chou MM
Am. J. Obstet. Gynecol., 2006;194(2):564-71.
Species: Human
Sample Types: Tissue Homogenates
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Oncostatin M induces angiogenesis and cartilage degradation in rheumatoid arthritis synovial tissue and human cartilage cocultures.
Authors: Fearon U, Mullan R, Markham T, Connolly M, Sullivan S, Poole AR, FitzGerald O, Bresnihan B, Veale DJ
Arthritis Rheum., 2006;54(10):3152-62.
Species: Human
Sample Types: Cell Culture Supernates
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Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer.
Authors: Furstenberger G, von Moos R, Lucas R, Thurlimann B, Senn HJ, Hamacher J, Boneberg EM
Br. J. Cancer, 2006;94(4):524-31.
Species: Human
Sample Types: Serum
-
Vitreous levels of angiopoietin 2 and vascular endothelial growth factor in patients with proliferative diabetic retinopathy.
Authors: Watanabe D, Suzuma K, Suzuma I, Ohashi H, Ojima T, Takagi H
Am. J. Ophthalmol., 2005;139(3):476-81.
Species: Human
Sample Types: Vitreous Humor
-
IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
J. Immunol., 2005;175(9):6177-89.
Species: Human
Sample Types: Cell Culture Supernates
-
Bi-directional cell contact-dependent regulation of gene expression between endothelial cells and osteoblasts in a three-dimensional spheroidal coculture model.
Authors: Stahl A, Wenger A, Weber H, Stark GB, Augustin HG, Finkenzeller G
Biochem. Biophys. Res. Commun., 2004;322(2):684-92.
Species: Human
Sample Types: Cell Culture Supernates
-
Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis*
Authors: Ricciuto DR, Dos Santos CC, Hawkes M, Toltl LJ, Conroy AL, Rajwans N, Lafferty EI, Cook DJ, Fox-Robichaud A, Kahnamoui K, Kain KC, Liaw PC, Liles WC
Crit. Care Med., 0;0(0):.
Species: Human
Sample Types: Plasma
-
Evaluation of plasma angiopoietin-2 and vascular endothelial growth factor in healthy dogs and dogs with systemic inflammatory response syndrome or sepsis.
Authors: Konig M, Nentwig A, Marti E, Mirkovitch J, Adamik K, Schuller S
J Vet Intern Med, 0;0(0):.
Species: Canine
Sample Types: Plasma
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Average Rating: 4.3 (Based on 3 Reviews)
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another excellent ELISA from R and D