Human Angiopoietin-like Protein 8/Betatrophin Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB8548U Datasheet / COA / SDS

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FAB8548U-100UG

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All Angiopoietin-like Protein 8/Betatrophin Antibodies

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Human Angiopoietin-like Protein 8/Betatrophin Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Angiopoietin-like Protein 8/Betatrophin in direct ELISA and Western Blots.

Source

Monoclonal Mouse IgG1 Clone # 910248

Purification

Protein A or G purified

Immunogen

Human Angiopoietin-like Protein 8/Betatrophin synthetic peptide with sequences corresponding to the N-term region
Accession # Q6UXH0

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Angiopoietin-like Protein 8/Betatrophin

Betatrophin also known as C19orf80, ANGPTL8, and TD26, is a secreted hormone protein. It is 198 amino acids (aa) in length, and shares 72% aa identity with mouse Betatrophin. It is primarily expressed in the liver and adipose tissue and has been shown to be increased in the plasma of diabetic patients. Additionally, Betatrophin has been demonstrated to increase the proliferation of beta cells in the pancreas of mice.

Entrez Gene IDs

55908 (Human); 624219 (Mouse); 100361444 (Rat)

Alternate Names

Angiopoietin like Protein 8; Angiopoietin-like Protein 8; ANGPTL8; Betatrophin; C19orf80; chromosome 19 open reading frame 80; Gm6484; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26; Lipasin; PRO1185; PVPA599; RIFL; TD26; UNQ599