Human beta -I Tubulin Alexa Fluor™ Plus 405‑conjugated Antibody

R&D Systems | Catalog # FAB8527AFP405

R&D Systems
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot, Immunocytochemistry

Label

Alexa Fluor Plus 405 (Excitation = 404 nm, Emission = 455 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 923425
View all beta-I Tubulin Primary Antibodies »

Product Specifications

Specificity

Detects human beta -I Tubulin in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human beta -I Tubulin Alexa Fluor™ Plus 405‑conjugated Antibody

Application
Recommended Usage

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: beta-I Tubulin

beta -tubulin is a 50 kDa cytoskeletal protein which is the a major component of neuronal processes: axons, dendrites, and dendritic spines. beta -tubulin is represented by different isoforms including beta -I, beta -II, beta -III, and beta -IV. Elimination of beta -I isoform will decrease the viability of neuroblastoma cells. Formation of actin tubules may be directly inhibited by beta -I isoform which results in decreasing cellular adhesion. beta -I Tubulin levels in different brain regions of schizophrenia patients  undergo noticeable changes suggesting that this isoform may have a specific role in the pathophysiology of this illness by affecting actin tubule formation which is required for cell division and differentiation.

Long Name

Tubulin, Beta 1 Class VI

Alternate Names

betaI Tubulin, TUBB1

Entrez Gene IDs

81027 (Human); 545486 (Mouse); 679312 (Rat)

Gene Symbol

TUBB1

UniProt

Q9H4B7

Additional beta-I Tubulin Products

Product Documents for Human beta -I Tubulin Alexa Fluor™ Plus 405‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human beta -I Tubulin Alexa Fluor™ Plus 405‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

Acute Myeloid Leukemia
Microtubules

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Protocols

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FAQs

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