Human Calcitonin R (NP_001733) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC0108
R&D Systems VersaClone cDNA Plasmids
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Human Calcitonin R (NP_001733) VersaClone cDNA Summary

The Calcitonin Receptor (CALCR) is a glycosylated 70 kDa seven-transmembrane G protein-coupled receptor that mediates the hypocalcemic effects of the peptide hormone, calcitonin. CALCR activation inhibits osteoclast-mediated bone resorption and enhances renal calcium excretion. CALCR polymorphisms and mutations have been associated with several bone disorders. Alternate splicing of the Calcitonin Receptor results in the deletion of 16 aa in the first cytoplasmic loop or 23 aa in the first extracellular region. Human CALCR shares 70% - 72% aa sequence identity with mouse and rat CACLR.

Specifications

Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

Background: Calcitonin R

Long Name
Calcitonin Receptor
Entrez Gene IDs
799 (Human); 12311 (Mouse); 116506 (Rat)
Alternate Names
Calcitonin R; calcitonin receptor; CalcitoninR; CALCR; CRT; CTR; CT-R; CTR1

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Tocris Peptides

Amylin (rat)

CRSP-1

Pramlintide

Tocris Small Molecules

SUN-B 8155

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