The Calcitonin Receptor (CALCR) is a glycosylated 70 kDa seven-transmembrane G protein-coupled receptor that mediates the hypocalcemic effects of the peptide hormone, calcitonin. CALCR activation inhibits osteoclast-mediated bone resorption and enhances renal calcium excretion. CALCR polymorphisms and mutations have been associated with several bone disorders. Alternate splicing of the Calcitonin Receptor results in the deletion of 16 aa in the first cytoplasmic loop or 23 aa in the first extracellular region. Human CALCR shares 70% - 72% aa sequence identity with mouse and rat CACLR.
Human Calcitonin R (NP_001733) VersaClone cDNA
R&D Systems | Catalog # RDC0108
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Calcitonin R
Long Name
Calcitonin Receptor
Alternate Names
CalcitoninR, CALCR, CT-R
Gene Symbol
CALCR
UniProt
Additional Calcitonin R Products
Product Documents for Human Calcitonin R (NP_001733) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human Calcitonin R (NP_001733) VersaClone cDNA
For research use only
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