Human Catalase Alexa Fluor® 405-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB3398V-100UG

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Human Catalase Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human Catalase in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse Catalase or recombinant human Serpin C1 is observed.
Source
Monoclonal Mouse IgG1 Clone # 724810
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human Catalase
Met1-Leu527
Accession # P04040
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 
Knockout Validated
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Catalase

Cells have evolved complex mechanisms to maintain redox balance and defend against oxidative stress. Catalase is a tetrameric enzyme comprised of four 60 kDa subunits. Catalase is typically localized in the peroxisome where it functions as an antioxidant, protecting cells from damage due to oxidative stress. Catalase converts reactive oxygen species, such as H2O2, into water and O2. Human Catalase shares 89% homology to mouse and rat Catalase. The cells redox environment can serve as an important signaling switch or trigger to initiate a number of cellular processes, including gene expression, differentiation, proliferation and apoptosis.

Entrez Gene IDs
847 (Human); 12359 (Mouse); 24248 (Rat)
Alternate Names
Cas1; CAT; Catalase; Cs-1; EC 1.11.1.6; MGC138422; MGC138424

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