Human CCR4 Alexa Fluor® 700-conjugated Antibody

FAB1567N 1 Citation Datasheet / COA / SDS

Clone 205410 was used by HLDA to establish CD designation

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FAB1567N-100UG

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Human CCR4 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects CCR4 on human PBLs and platelets.

Source

Monoclonal Mouse IgG2b Clone # 205410

Immunogen

Human CCR4 transfectants
Met1-Leu360
Accession # P51679

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

0.25-1 µg/10⁶ cells

Human peripheral blood mononuclear cells (PBMCs)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CCR4

CCR4 is a G protein-linked seven transmembrane domain chemokine receptor that binds the chemokines CCL17/TARC and CCL22/MDC. Current evidence suggests that CCR4 expression is associated with Th-2 type T cells and with platelets. CCR4 expression has also been reported in mature dendritic cells.

Entrez Gene IDs

1233 (Human); 12773 (Mouse); 171054 (Rat); 403541 (Canine); 102120178 (Cynomolgus Monkey)

Alternate Names

C-C chemokine receptor type 4; C-C CKR-4; CC-CKR-4HGCN:14099; CCR4; CCR-4; CD194 antigen; CD194; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; ChemR13; CKR4MGC88293; CMKBR4k5-5; K5-5

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Human CCR4 Alexa Fluor® 700-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Chimeric antigen receptor-modified human regulatory T cells that constitutively express IL-10 maintain their phenotype and are potently suppressive
Authors: YR Mohseni, A Saleem, SL Tung, C Dudreuilh, C Lang, Q Peng, A Volpe, G Adigbli, A Cross, J Hester, F Farzaneh, C Scotta, RI Lechler, F Issa, GO Fruhwirth, G Lombardi
European Journal of Immunology, 2021;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry