Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Sheep IgG
View all Complement Factor H-related 1/CFHR1 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Complement Factor H-related 1/CFHR1
Glu19-Ala328
Accession # Q03591

Specificity

Detects human Complement Factor H-related 1/CFHR1 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross‑reactivity with recombinant human (rh) FHR2 is observed and approximately 15% cross-reactivity with rhFHR5 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Human Complement Factor H-related 1/CFHR1 Antibody

Application
Recommended Usage

Immunoprecipitation

25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Human
Complement Factor H-related 1/CFHR1, see our available Western blot detection antibodies

Western Blot

0.1 µg/mL
Sample: Recombinant Human Complement Factor H-related 1/CFHR1

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Complement Factor H-related 1/CFHR1

FHR1 (Complement Factor H-related protein 1) is a 43 kDa, secreted member of the factor H family of glycoproteins. It is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human FHR1 is 312 amino acids (aa) in length. It contains five, approximately 60 aa SCRs (short consensus repeats/CCPs/SUSHI repeats) that basically constitute the entire molecule. FHR1 may play a role in lipoprotein complexes that bind PMNs to LPS. There is no reported rodent counterpart to FHR1. Over aa 19‑143 of the FHR1 precursor, human FHR2 and FHR5 show 98% and 86% aa identity, respectively.

Alternate Names

BTA, CFHR1, Complement Factor Hrelated 1, FHR1

Entrez Gene IDs

3078 (Human)

Gene Symbol

CFHR1

UniProt

Q03591

Additional Complement Factor H-related 1/CFHR1 Products

Product Documents for Human Complement Factor H-related 1/CFHR1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human Complement Factor H-related 1/CFHR1 Antibody

For research use only

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