Human Dopamine D1 R/DRD1 PE-conjugated Antibody

FAB8276P has been discontinued. View all Dopamine D1 R/DRD1 products.
    
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  • Species Reactivity
    Human
  • Specificity
    Stains human Dopamine D1 R/DRD1 transfected cells but not irrelevant transfectants in flow cytometry.
  • Source
    Monoclonal Mouse IgG2A Clone # 887438
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    NS0 mouse myeloma cell line transfected with human Dopamine D1 R/DRD1
    Met1-Thr446
    Accession # P21728
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
    Phycoerythrin
Product Datasheets

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Applications
  •  
    Recommended
    Concentration
    Sample
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Example
Detection of Dopamine D1 R/DRD1 in HEK293 Human Cell Line Transfected with Human Dopamine D1 R/DRD1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with (A) human Dopamine D1 R/DRD1 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human Dopamine D1 R/DRD1 PE‑conjugated Monoclonal Antibody (Catalog # FAB8276P) and. Quadrant markers were set based on control antibody staining (Catalog # IC003P). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Dopamine D1 R/DRD1

Dopamine Receptor D1 (DRD1) is a 50 kDa member of class 1 GPCR superfamily and is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. DRD1 is associated with nicotine dependence, schizophrenia, and systolic blood pressure levels.

  • Long Name:
    Dopamine D1 Receptor
  • Entrez Gene IDs:
    1812 (Human); 13488 (Mouse); 24316 (Rat)
  • Alternate Names:
    D(1A) dopamine receptor; D1DR; DADR; Dopamine D1 R; Dopamine D1 receptor; Dopamine D1R; dopamine receptor D1; DRD1; DRD1A
Related Research Areas

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