Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Rat

Applications

Validated:

Western Blot

Cited:

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all Exostosin-like 3/EXTL3 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Exostosin-like 3/EXTL3 Lumenal Domain
Thr52-Ile919
Accession # O43909

Specificity

Detects human Exostosin-like 3/EXTL3 Lumenal Domain in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Exostosin‑like 3/EXTL3 Lumenal Domain Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human Exostosin-like 3/EXTL3 Lumenal Domain

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Exostosin-like 3/EXTL3

Exostosin-like 3 (EXTL3) is an ER-resident type II transmembrane protein belonging to the EXT family of tumor suppressor genes. EXT family members are glycosyl transferases that are involved in the synthesis of the glycosaminoglycan chains of heparan sulfate proteoglycans. EXTL3 was also reported to be a receptor for the REG protein, a pancreatic beta-cell regeneration factor. The lumenal domains of human, mouse and rat share 97% amino acid sequence identity.

Alternate Names

Exostosin like 3, EXTL3

Entrez Gene IDs

2137 (Human)

Gene Symbol

EXTL3

UniProt

O43909

Additional Exostosin-like 3/EXTL3 Products

Product Documents for Human Exostosin‑like 3/EXTL3 Lumenal Domain Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human Exostosin‑like 3/EXTL3 Lumenal Domain Antibody

For research use only

Related Research Areas

Glycobiology-related Enzymes

Citations for Human Exostosin‑like 3/EXTL3 Lumenal Domain Antibody

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