Glycobiology-related Enzymes

Enzymes play several crucial roles in glycobiology. For instance, transferases are involved in complex carbohydrate synthesis. In addition, carbohydrates are metabolized by glycosidases and modified by a variety of enzymes including sulfatases. As a result, these enzymes may be utilized as useful tools to understand carbohydrate structure and function. For example, they may be used to delineate or determine the structure of an oligosaccharide of interest, or modulate carbohydrate structure to see how it impacts its biological functions.

Products by Category

Carbohydrate Kinases

ADKFAM20BFructosamine-3-kinase/FN3KGlucokinase/GCKHexokinase 1
Hexokinase 1/2Hexokinase 2Hexokinase ActivatorsKetohexokinaseN-Acetylmannosamine Kinase/GNE
N-Acetyl-D-Glucosamine Kinase/NAGKPFKFB3PFKFB3 InhibitorsPFKFB4Xylulokinase/XYLB

Carbohydrate Sulfotransferases

Carbohydrate Sulfotransferase 1/CHST1Carbohydrate Sulfotransferase 2/CHST2Carbohydrate Sulfotransferase 3/CHST3Carbohydrate Sulfotransferase 4/CHST4Carbohydrate Sulfotransferase 5/CHST5
Carbohydrate Sulfotransferase 6/CHST6Carbohydrate Sulfotransferase 7/CHST7Carbohydrate Sulfotransferase 10/CHST10Carbohydrate Sulfotransferase 15/CHST15Galactose-3-O-sulfotransferase 2/GAL3ST2
Heparan Sulfate 2-O-Sulfotransferase 1/HS2ST1Heparan Sulfate 3-O-Sulfotransferase 1/HS3ST1Heparan Sulfate 3-O-Sulfotransferase 4/HS3ST4Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1Heparan Sulfate 6-O-Sulfotransferase 2/HS6ST2
Heparan Sulfate 6-O-Sulfotransferase 3/HS6ST3Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3N-Deacetylase/N-Sulfotransferase 1/NDST1N-Deacetylase/N-Sulfotransferase 2/NDST2 

Fetuins

Fetuin A/AHSGFetuin B

Fucosyltransferases

FucosyltransferaseFucosyltransferase 2/FUT2Fucosyltransferase 3/FUT3Fucosyltransferase 3/5 (FUT3/5)Fucosyltransferase 5/FUT5
Fucosyltransferase 7/FUT7Fucosyltransferase 8/FUT8Fucosyltransferase 9/FUT9Fucosyltransferase 11/FUT11Protein O-Fucosyltransferase 1/POFUT1

Galactosyl Transferases

alpha3GalT/GGTA1B3GalT2B3GalT4B3GalT5
beta-1,4-Galactosyltransferase 1/B4GalT1beta-1,4-Galactosyltransferase 2/B4GalT2Beta-1,4-Galactosyltransferase 7/B4GalT7C1GalT1
C1GalT1C1Galactosyltransferase 1/GALT-1Blood Group B Transferase/GTB 

GalNAc Transferases

B3GALNT1B3GALNT2GM2/GD2 Synthase/ B4GALNT1B4GALNT2B4GALNT3
B4GALNT4CSGalNAcT-2Polypeptide GalNAc Transferase 1/GALNT1Polypeptide GalNAc Transferase 2/GALNT2Polypeptide GalNAc Transferase 3/GALNT3
Polypeptide GalNAc Transferase 4/GALNT4Polypeptide GalNAc Transferase 7/GALNT7Polypeptide GalNAc Transferase 10/GALNT10Polypeptide GalNAc Transferase 11/GALNT11Polypeptide GalNAc Transferase 12/GALNT12
Polypeptide GalNAc Transferase 13/GALNT13Polypeptide GalNAc Transferase 14/GALNT14GALNTL1  

GlcNAc Transferases

Alpha-1,4-N-Acetylglucosaminyltransferase 4/A4GNTBeta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2Beta-1,3-N-Acetylglucosaminyltransferase 3/B3GNT3Beta-1,3-N-Acetylglucosaminyltransferase 4/B3GNT4Beta-1,3-N-Acetylglucosaminyltransferase 6/B3GNT6
beta-1,4-Glucuronyltransferase 1/B4GAT1C2GNT3/GCNT4EOGTExostosin 1Exostosin 1/2 Heterodimer
Exostosin 2Exostosin-like 1/EXTL1Exostosin-like 2/EXTL2Exostosin-like 3/EXTL3Glucosaminyl (N-acetyl) Transferase 1/GCNT1
Glucosaminyl (N-acetyl) Transferase 2/GCNT2Lunatic Fringe/LFNGMFNGN-Acetylglucosaminyltransferase I/MGAT1N-Acetylglucosaminyltransferase 2/MGAT2
N-Acetylglucosaminyltransferase III/MGAT3MGAT4AN-Acetylglucosaminyltransferase V/MGAT5Notch EGF20O-GlcNAc Transferase/OGT
POMGNT1RFNG   

Glucosyltransferases

Protein O-Glucosyltransferase 1/POGLUT1Toxin A/TcdAToxin B/TcdB

Glucuronosyltransferases

beta-1,3-Glucuronyltransferase 1/B3GAT1Beta-1,3-Glucuronyltransferase 2/B3GAT2beta-1,3-Glucuronyltransferase 3/B3GAT3Glucuronosyltransferase 1A1/UGT1A1UGT1A9

Glycosidases

alpha-Galactosidase A/GLAalpha-N-acetylgalactosaminidase/NAGAalpha-L-FucosidaseTissue alpha-L-Fucosidase/FUCA1AMCase/CHIA
beta-Galactosidase-1/GLB1beta-Glucuronidase/GUSBbeta (1-3)-Galactosidasebeta (1-4)-GalactosidaseChitinase 3-like 1/YKL-40
Chitinase 3-like 2Chitobiase/CTBSChitotriosidase/CHIT1Chondroitin B Lyase/Chondroitinase BChondroitinase ABC
Chondroitinase ACCytosolic beta-Glucosidase/GBA3Endo-beta-GalactosidaseEndo-beta-N-acetylglucosaminidase F1/Endo F1Endo-beta-N-acetylglucosaminidase F3/Endo F3
Endo-beta-N-acetylglucosaminidase H/Endo HEndo-beta-N-acetylglucosaminidase S2/Endo S2Plasma alpha-L-Fucosidase/FUCA2Galactosylceramidase/GALCGlucosylceramidase/GBA
Heparanase/HPSEHeparinase IHeparinase IIHeparinase IIIHexosaminidase A/HEXA
Hexosaminidase B/HEXBHyaluronan LyaseHyaluronidase 1/HYAL1Hyaluronidase 2/HYAL2Hyaluronidase 4/HYAL4
alpha-L-Iduronidase/IDUAKlothoKlotho betaLactase-like Protein/LCTLLysosomal alpha-Glucosidase
MAN1A1MAN1A2MAN2A1MAN2B1MBD4
alpha-N-acetylglucosaminidase/NAGLUNEU-1/Sialidase-1O-GlcNAcase/OGAO-GlycosidasePNGase At
PNGase FSPAM1YM1/Chitinase 3-like 3  

Glycosyltransferase Assays and Substrates

Alkyne ConjugatesFucose DetectionGalNAc Detection
GlcNAc DetectionGlycosyltransferase Assay KitSialic Acid Detection

Mucins

CA125/MUC16CA15-3/MUC-1CD43CD164CD300g/Nepmucin
CX3CL1/FractalkineEndoglycan/PODXL2EndomucinMCAM/CD146MUC-1
MUC-19MUC-4PodoplaninPoriminTIM-1/KIM-1/HAVCR
TIM-2TIM-3TIM-4TIM-5TIM-6

Neuraminidases

Bacterial NeuraminidaseViral Neuraminidase

Pentosyltransferases

Protein Sulfotransferases

Tyrosylprotein Sulfotransferase 1/TPST1Tyrosylprotein Sulfotransferase 2/TPST2

Proteoglycan Regulators

Arylsulfatase A/ARSAArylsulfatase B/ARSBArylsulfatase G/ARSGbeta-Glucuronidase/GUSBCarbohydrate Sulfotransferase 15/CHST15
Exostosin 1Exostosin 1/2 HeterodimerExostosin 2Exostosin-like 1/EXTL1Exostosin-like 2/EXTL2
Exostosin-like 3/EXTL3FAM20BGlucosamine (N-acetyl)-6-Sulfatase/GNSHeparan Sulfate 2-O-Sulfotransferase 1/HS2ST1Heparan Sulfate 3-O-Sulfotransferase 1/HS3ST1
Heparan Sulfate 3-O-Sulfotransferase 4/HS3ST4Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1Heparan Sulfate 6-O-Sulfotransferase 2/HS6ST2Heparan Sulfate 6-O-Sulfotransferase 3/HS6ST3Heparanase/HPSE
Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3Iduronate 2-Sulfatase/IDSN-Deacetylase/N-Sulfotransferase 1/NDST1N-Deacetylase/N-Sulfotransferase 2/NDST2Sulfatase-2/SULF2
WARP    

Sialyltransferases

Sialyltransferase Assay KitST3 beta-Gal alpha-2,3-Sialyltransferase 1/ST3GAL1ST3 beta-Gal alpha-2,3-Sialyltransferase 2/ST3GAL2ST3GAL3ST3GAL4
ST3GAL5/GM3 SynthaseST3GAL6ST6 Gal Sialyltransferase 1/ST6GAL1ST6 Sialyltransferase 2/ST6GALNAC2ST6GALNAC4
ST6 GalNAc alpha-2,6-sialyltransferaseV/ST6GALNAC5ST6 Sialyltransferase 6/ST6GALNAC6ST6 Gal Sialyltransferase 2/ST6GAL2ST6 Sialyltransferase 1/ST6GALNAC1ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1
ST8 alpha-2,8-Sialyltransferase 8B/ST8SIA2ST8 alpha-2,8-Sialyltransferase 4/ST8SIA4ST8 alpha-2,8-Sialyltransferase 6/ST8SIA6  

Sulfatase Modifying Factors

Sulfatase Modifying Factor 1/SUMF1Sulfatase Modifying Factor 2/SUMF2

Sulfatases

Arylsulfatase A/ARSAArylsulfatase B/ARSBArylsulfatase G/ARSGGlucosamine (N-acetyl)-6-Sulfatase/GNS
Iduronate 2-Sulfatase/IDSN-Acetylgalactosamine-6-Sulfatase/GALNSSulfamidase/SGSHSulfatase-2/SULF2

Sulfotransferase Assays and Substrates

PAPSSulfotransferase Assay Kit

Other Glycobiology-related Enzymes

MAN1A1MAN1A2MAN2A1MAN2B1
6-Phosphogluconate Dehydrogenase/PGDMuscle Phosphofructokinase/PFKMPKM2TIGAR/C12orf5

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