Human FCRL4/FcRH4 Alexa Fluor® 488-conjugated Antibody

Catalog # Availability Size / Price Qty
AF2426G-100UG

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Human FCRL4/FcRH4 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human FCRL4/FcRH4 in direct ELISAs. In direct ELISAs, less than 2% cross‑reactivity with recombinant human (rh) IRTA2, rhIRTA3, rhIRTA4, and rhIRTA5 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human FCRL4/FcRH4
Gln16-Asp385
Accession # Q96PJ5
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FCRL4/FcRH4

FcRH4, also known as IRTA1 (immunoglobulin superfamily receptor translocation associated 1), is a member of the Ig superfamily. It shares sequence homology with the classical Fc receptors. FcRH4 is preferentially expressed in B cells and contains three potential ITIM motifs in its extracellular domain. The gene for FcRH4 is localized to the human chromosome Iq 21‑23 region, a hotspot for translocation events.

Long Name
Fc Receptor-like protein 4
Entrez Gene IDs
83417 (Human)
Alternate Names
CD307d antigen; CD307d; Fc receptor homolog 4; Fc receptor-like 4; FcRH4; FCRH4Fc receptor-like protein 4; FCRL4; FcR-like protein 4; hIFGP2; IFGP family protein 2; IFGP2; IGFP2; Immune receptor translocation-associated protein 1; immunoglobulin superfamily Fc receptor, gp42; immunoglobulin superfamily receptor translocation associated 1; IRTA1; IRTA1MGC150523; MGC150522

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