Human FCRL4/FcRH4 Biotinylated Antibody

Catalog #: BAF2426
1 Citation Datasheet / COA / SDS

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BAF2426

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Citations (1)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human FCRL4/FcRH4 Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human FCRL4/FcRH4 in Western blots. In Western blots, less than 2% cross-reactivity with recombinant human (rh) IRTA2, rhIRTA3, rhIRTA4, and rhIRTA5 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FCRL4/FcRH4
Gln16-Asp385
Accession # Q96PJ5

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human FCRL4/FcRH4

Immunohistochemistry

5-15 µg/mL

Immersion fixed paraffin-embedded sections of human small intestine (Peyer's patch) and tonsil

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available

Reconstitution Buffer 1 (PBS)

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FCRL4/FcRH4

FcRH4, also known as IRTA1 (immunoglobulin superfamily receptor translocation associated 1), is a member of the Ig superfamily. It shares sequence homology with the classical Fc receptors. FcRH4 is preferentially expressed in B cells and contains three potential ITIM motifs in its extracellular domain. The gene for FcRH4 is localized to the human chromosome Iq 21‑23 region, a hotspot for translocation events.

Long Name

Fc Receptor-like protein 4

Entrez Gene IDs

83417 (Human)

Alternate Names

CD307d antigen; CD307d; Fc receptor homolog 4; Fc receptor-like 4; FcRH4; FCRH4Fc receptor-like protein 4; FCRL4; FcR-like protein 4; hIFGP2; IFGP family protein 2; IFGP2; IGFP2; Immune receptor translocation-associated protein 1; immunoglobulin superfamily Fc receptor, gp42; immunoglobulin superfamily receptor translocation associated 1; IRTA1; IRTA1MGC150523; MGC150522

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for Human FCRL4/FcRH4 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.
Authors: Kazemi T, Asgarian-Omran H, Hojjat-Farsangi M, Shabani M, Memarian A, Sharifian RA, Razavi SM, Jeddi-Tehrani M, Rabbani H, Shokri F
Int. J. Cancer, 2008;123(9):2113-9.
Species: Human
Sample Types: Whole Cells
Applications: ICC