Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all FGF-17 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human FGF-17
Thr23-Thr216
Accession # O60258

Specificity

Detects human FGF-17 in Western blots. In Western blots, approximately 10% cross‑reactivity with recombinant human (rh) FGF‑8b and recombinant mouse FGF-8c is observed and no cross-reactivity with rhFGF-4, rhFGF-5, rhFGF-6, rhFGF-7, and rhFGF-10 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human FGF-17 Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human FGF‑17 (Catalog # 319-FG)

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: FGF-17

Fibroblast growth factors (FGFs) play multiple biological functions including angiogenesis, mitogenesis, cellular differentiation and wound repairing. All members of the FGF family have a conserved approximately 120 amino acid core with 30‑70% identity. Among FGF family members, FGF-17 is most similar to FGF-8 (60% sequence identity) and FGF-18 (50% sequence identity). The mRNA of FGF-17 was found in midgestation of embryo and multiple adult tissues, and is preferentially expressed in specific sites, such as embryonic brain, developing skeleton and arteries. Human FGF‑17 shares 98.6% amino acid (aa) sequence identity with mouse FGF‑17. Rat FGF‑17 shares 100% aa sequence identity with mouse FGF‑17.

References

  1. Hoshikawa, M. et al. (1998) Biochem. Biophys. Res. Commun. 244:187.
  2. Xu, J. et al. (1999) Mech. Dev. 83:165.

Long Name

Fibroblast Growth Factor 17

Alternate Names

FGF17

Entrez Gene IDs

8822 (Human); 14171 (Mouse)

Gene Symbol

FGF17

UniProt

O60258

Additional FGF-17 Products

Product Documents for Human FGF-17 Biotinylated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human FGF-17 Biotinylated Antibody

For research use only

Related Research Areas

FGF Family
FGF Ligands

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