Human FOXL2 Alexa Fluor® 350-conjugated Antibody Summary
Accession # P58012
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
Background: FOXL2
FOXL2 is a forkhead transcription factor which plays a role in ovarian development and function. It is transcribed very early in somatic cells of the developing gonad (before sex determination) and its expression persists in the follicular cells of the adult ovary. Females missing the FOXL2 gene appear to be male. FOXL2 prevents transdifferentiation of an adult ovary to a testis. Overexpression of FOXL2 has been implicated in endometriosis with 3-fold higher mRNA expression in endometriosis than in healthy endometrium.
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