Human FOXL2 Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB10396G Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB10396G-100UG

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Human FOXL2 Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human FOXL2 in direct ELISAs.
Source
Monoclonal Mouse IgG2b Clone # 1019104
Purification
Protein A or G purified
Immunogen
Synthetic peptide containing human FOXL2
Accession # P58012
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FOXL2

FOXL2 is a forkhead transcription factor which plays a role in ovarian development and function. It is transcribed very early in somatic cells of the developing gonad (before sex determination) and its expression persists in the follicular cells of the adult ovary. Females missing the FOXL2 gene appear to be male.  FOXL2 prevents transdifferentiation of an adult ovary to a testis.  Overexpression of FOXL2 has been implicated in endometriosis with 3-fold higher mRNA expression in endometriosis than in healthy endometrium.

Long Name
Forkhead Box L2
Entrez Gene IDs
668 (Human); 26927 (Mouse)
Alternate Names
BPES; BPES1; BPES1PINTO; forkhead box L2; forkhead box protein L2; forkhead transcription factor FOXL2; FOXL2; PFRK; PINTO; POF3

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