Human GLP-2R APC-conjugated Antibody
Human GLP-2R APC-conjugated Antibody Summary
Met1-Ile553
Accession # O95838
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of GLP‑2R in NS0 Mouse Cell Line Transfected with Human GLP-2R by Flow Cytometry. NS0 mouse myeloma cell line transfected with human GLP-2R was stained with Mouse Anti-Human GLP-2R APC-conjugated Monoclonal Antibody (Catalog # FAB4285A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: GLP-2R
GLP-2R is a member of the class II glucagon-secretin G protein-coupled receptor superfamily. It is expressed on enteroendocrine cells in the gut where it mediates the positive effects of GLP2 on villus height, crypt depth and intestinal energy absorbtion. After stimulating a cAMP response, lipid raft-dependent internalization of GLP‑2R results in rapid desensitization to GLP2. Extracellular portions of human GLP-2R show approximately 80% amino acid identity with corresponding regions of mouse GLP-2R.
Product Datasheets
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