Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Antibody

Name: Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Antibody
Brand: R&D Systems
SKU: MAB11481
Price: 479 USD
Availability: InStock

R&D Systems | Catalog # MAB11481

Submit a review

Product Documents

Recombinant Monoclonal Antibody For Research Use Only

View Available Conjugates

100% Guarantee

Product Specifications
Scientific Data
Applications
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG₁ Clone # Hu209

View all IL-4R alpha Primary Antibodies »

Product Specifications

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL‑4 R
Gly24-His232
Accession # P24394

Specificity

Detects human IL‑4 R alpha in ELISAs.

Clonality

Monoclonal

Host

Human

Isotype

IgG₁

Scientific Data Images for Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Antibody

Human IL-4R alpha ELISA Standard Curve

Direct ELISA binding curve demonstrating the recognition of Human Anti-Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Monoclonal Antibody (Catalog # MAB11481) to IL-4R alpha. The target protein was coated onto the microplate well surface, followed by binding of the antibody. A goat anti-human HRP conjugate was used for detection.

Applications for Human IL-4R alpha (Research Grade Dupilumab Biosimilar) Antibody

Application

Recommended Usage

ELISA

This antibody functions as an ELISA detection antibody for the specific antigen in direct ELISA. Colorimetric detection is performed after addition of a suitable substrate.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from ascites

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: IL-4R alpha

Interleukin 4 receptor (IL-4 R) is the transmembrane ligand binding subunit of the heterodimeric IL-4 receptor complex. In the type I receptor complex, IL-4 R associates with the common gamma chain, whereas in the type II receptor complex, it associates with IL-13 R alpha 1. IL-4 R is expressed by B cells, T cells, monocytes and macrophages.