Human IL-8/CXCL8 Quantikine ELISA Kit D8000C: R&D Systems
  • Assay Type
    Solid Phase Sandwich ELISA
  • Format
    96-well strip plate
  • Assay Length
    3.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL), Citrate Plasma (50 uL)
  • Sensitivity
    7.5 pg/mL
  • Assay Range
    31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)
  • Specificity
    Natural and recombinant human IL-8
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    No significant interference observed with available related molecules.
Control Available
QC23, Quantikine Immunoassay Control Group 8 - Please Inquire
Product Summary
The Quantikine Human IL-8 Immunoassay is a 3.5 hour solid phase ELISA designed to measure human IL-8 in cell culture supernates, serum, and plasma. It is based on antibodies raised against the 72 aa variant of human IL-8 derived from E. coli. It is calibrated with the same recombinant factor. This immunoassay accurately quantitates recombinant human IL-8. Measurement of natural human IL-8 or the 77 aa variant of human IL-8 gave results parallel to the standard curves obtained using the E. coli-expressed Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-8.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays) hree samples of known concentration were tested in separate assays to assess inter-assay precision.
Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Intra-Assay Precision Inter-Assay Precision
Sample123123
n202020202020
Mean16852610931965811160
Standard Deviation9.428.670.714.556.670.2
CV%5.65.46.57.49.76.1

Cell Culture Supernates
Intra-Assay Precision Inter-Assay Precision
Sample123123
n202020202020
Mean115386802132410817
Standard Deviation5.31737.910.72842.4
CV%4.64.44.78.16.85.2

Recovery

The recovery of IL-8 spiked to three different levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=5) 98 85-114
Citrate Plasma (n=5) 105 95-114
EDTA Plasma (n=5) 103 97-111
Heparin Plasma (n=5) 102 92-107
Serum (n=5) 98 88-106
Linearity
To assess the linearity of the assay, samples were spiked with high concentrations of IL-8 in various matrices and diluted with the appropriate Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Human IL-8/CXCL8 Quantikine ELISA Kit
Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: IL-8/CXCL8
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
    • Long Name
      Interleukin 8
    • Entrez Gene IDs
      3576 (Human); 396880 (Porcine); 403850 (Canine); 493836 (Feline);
    • Alternate Names
      3-10C; AMCF-I; C-X-C motif chemokine 8; CXCL8; CXCL8SCYB8; Emoctakin; GCP1; GCP-1TSG-1; IL8; IL-8; interleukin 8; K60; LAI; LECT; MDNCF; MDNCFb-ENAP; member 8; MONAPGCP1; NAP1; NAP-1NAP1; NCF; Neutrophil-activating protein 1; Protein 3-10C; T cell chemotactic factor; T-cell chemotactic factor; TCF; TSG1;
    Related Research Areas
    Assay Procedure
    Refer to the product for complete assay procedure.

    Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
    1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
    2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

    3. 100 µL Assay Diluent
    4.   Add 100 µL of Assay Diluent to each well.

    5. 50 µL Standard, Control, or Sample
    6.   Add 50 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
    7.   Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.

    8. 100 µL Conjugate
    9.   Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 1 hour.
    10.   Aspirate and wash 4 times.

    11. 200 µL Substrate Solution
    12.   Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.

    13. 50 µL Stop Solution
    14.   Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
    Citations:

    R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

    229 Citations: Showing 1 - 10
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    Species
    Sample Type
    1. Substance P enhances lactic acid and tyramine production in Enterococcus faecalis V583 and promotes its cytotoxic effect on intestinal Caco-2/TC7 cells
      Authors: K Biaggini, V Borrel, S Szunerits, R Boukherrou, A N'Diaye, A Zébré, M Bonnin-Jus, G Duflos, M Feuilloley, D Drider, P Déchelotte, N Connil
      Gut Pathog, 2017;9(0):20.
      Species: Human
      Sample Type: Cell Culture Supernates
    2. Cigarette Smoke Impairs A2A Adenosine Receptor Mediated Wound Repair through Up-regulation of Duox-1 Expression
      Authors: Z Tian, H Zhang, J Dixon, N Traphagen, TA Wyatt, K Kharbanda, S Simet Chad, N Kolliputi, DS Allen-Gips
      Sci Rep, 2017;7(0):44405.
      Species: Human
      Sample Type: Cell Culture Supernates
    3. CD44 expression in endothelial colony-forming cells regulates neurovascular trophic effect
      Authors: S Sakimoto, V Marchetti, E Aguilar, K Lee, Y Usui, S Murinello, F Bucher, JK Trombley, R Fallon, R Wagey, C Peters, EL Scheppke, PD Westenskow, M Friedlande
      JCI Insight, 2017;2(2):e89906.
      Species: Human
      Sample Type: Cell Culture Supernates
    4. Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch
      PLoS ONE, 2016;11(4):e0153387.
      Species: Human
      Sample Type: Cell Culture Supernates
    5. Importance of the C-terminal histidine residues of Helicobacter pylori GroES for Toll-like receptor 4 binding and interleukin-8 cytokine production
      Sci Rep, 2016;6(0):37367.
      Species: Human
      Sample Type: Cell Culture Supernates
    6. Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system
      Oncogene, 2016;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    7. ROS-dependent HMGB1 secretion upregulates IL-8 in upper airway epithelial cells under hypoxic condition
      Mucosal Immunol, 2016;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    8. Differential diagnosis of lung cancer, its metastasis and chronic obstructive pulmonary disease based on serum Vegf, Il-8 and MMP-9
      Sci Rep, 2016;6(0):36065.
      Species: Human
      Sample Type: Serum
    9. A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains
      Authors: S Mairpady S, N Siemens, IR Monk, DB Mohan, S Mukundan, KC Krishnan, S Prabhakara, J Snäll, A Kearns, F Vandenesch, M Svensson, M Kotb, B Gopal, G Arakere, A Norrby-Teg
      Sci Rep, 2016;6(0):31360.
      Species: Human
      Sample Type: Tissue Culture Supernates
    10. Snake venom causes apoptosis by increasing the reactive oxygen species in colorectal and breast cancer cell lines
      Onco Targets Ther, 2016;9(0):6485-6498.
      Species: Human
      Sample Type: Cell Culture Supernates
    11. Acidic microenvironments induce lymphangiogenesis and IL-8 production via TRPV1 activation in human lymphatic endothelial cells
      Authors: Masako Nakanishi
      Exp Cell Res, 2016;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    12. The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection
      PLoS ONE, 2016;11(12):e0168102.
      Species: Human
      Sample Type: Cell Culture Supernates
    13. Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation
      PLoS ONE, 2016;11(11):e0165909.
      Species: Human
      Sample Type: Serum
    14. MicroRNAs regulate cytokine responses in gingival epithelial cells
      Infect Immun, 2016;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    15. The Antibiotic Polymyxin B Impairs the Interactions between Shiga Toxins and Human Neutrophils.
      Authors: Carnicelli D, Arfilli V, Ricci F, Velati C, Tazzari P, Brigotti M
      J Immunol, 2016;196(3):1177-85.
      Species: Human
      Sample Type: Cell Culture Supernates
    16. S100A9 expressed in ER(-)PgR(-) breast cancers induces inflammatory cytokines and is associated with an impaired overall survival.
      Authors: Bergenfelz C, Gaber A, Allaoui R, Mehmeti M, Jirstrom K, Leanderson T, Leandersson K
      Br J Cancer, 2015;113(8):1234-43.
      Species: Human
      Sample Type: Cell Culture Supernates
    17. SseK3 Is a Salmonella Effector That Binds TRIM32 and Modulates the Host's NF-kappaB Signalling Activity.
      Authors: Yang Z, Soderholm A, Lung T, Giogha C, Hill M, Brown N, Hartland E, Teasdale R
      PLoS ONE, 2015;10(9):e0138529.
      Species: Human
      Sample Type: Cell Culture Supernates
    18. The C-terminal disulfide bonds of Helicobacter pylori GroES are critical for IL-8 secretion via the TLR4-dependent pathway in gastric epithelial cells.
      Authors: Su Y, Yang J, Lee H, Sheu F, Hsu C, Lin S, Chow L
      J Immunol, 2015;194(8):3997-4007.
      Species: Human
      Sample Type: Cell Culture Supernates
    19. Production of IL-8, VEGF and Elastase by Circulating and Intraplaque Neutrophils in Patients with Carotid Atherosclerosis.
      Authors: Marino F, Tozzi M, Schembri L, Ferraro S, Tarallo A, Scanzano A, Legnaro M, Castelli P, Cosentino M
      PLoS ONE, 2015;10(4):e0124565.
      Species: Human
      Sample Type: Cell Culture Supernates
    20. The N terminus of type III secretion needle protein YscF from Yersinia pestis functions to modulate innate immune responses.
      Authors: Osei-Owusu P, Jessen Condry D, Toosky M, Roughead W, Bradley D, Nilles M
      Infect Immun, 2015;83(4):1507-22.
      Species: Human
      Sample Type: Cell Culture Supernates
    21. Pathogenic E. coli exploits SslE mucinase activity to translocate through the mucosal barrier and get access to host cells.
      Authors: Valeri M, Rossi Paccani S, Kasendra M, Nesta B, Serino L, Pizza M, Soriani M
      PLoS ONE, 2015;10(3):e0117486.
      Species: Human
      Sample Type: cell supernates
    22. Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer.
      Authors: Chuffa L, Fioruci-Fontanelli B, Mendes L, Ferreira Seiva F, Martinez M, Favaro W, Domeniconi R, Pinheiro P, Delazari Dos Santos L, Martinez F
      BMC Cancer, 2015;15(0):34.
      Species: Rat
      Sample Type: Tissue Supernate
    23. Dietary Omega-3 Fatty Acid Supplementation Reduces Inflammation in Obese Pregnant Women: A Randomized Double-Blind Controlled Clinical Trial.
      Authors: Haghiac M, Yang X, Presley L, Smith S, Dettelback S, Minium J, Belury M, Catalano P, Hauguel-De Mouzon S
      PLoS ONE, 2015;10(9):e0137309.
      Species: Human
      Sample Type: Plasma
    24. Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis.
      Authors: Wendling D, Abbas W, Godfrin-Valnet M, Kumar A, Guillot X, Khan K, Vidon C, Coquard L, Toussirot E, Prati C, Herbein G
      PLoS ONE, 2015;10(3):e0119981.
      Species: Human
      Sample Type: Serum
    25. CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18.
      Authors: Chu H, Rios C, Huang C, Wesolowska-Andersen A, Burchard E, O'Connor B, Fingerlin T, Nichols D, Reynolds S, Seibold M
      Gene Ther, 2015;22(10):822-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    26. The Alpha-Melanocyte-Stimulating Hormone Suppresses TLR2-Mediated Functional Responses through IRAK-M in Normal Human Keratinocytes.
      Authors: Ryu S, Johnson A, Park Y, Kim B, Norris D, Armstrong C, Song P
      PLoS ONE, 2015;10(8):e0136887.
      Species: Human
      Sample Type: Cell Culture Supernates
    27. Combining bevacizumab and chemoradiation in rectal cancer. Translational results of the AXEBeam trial.
      Authors: Verstraete M, Debucquoy A, Dekervel J, Van Pelt J, Verslype C, Devos E, Chiritescu G, Dumon K, D'Hoore A, Gevaert O, Sagaert X, Van Cutsem E, Haustermans K
      Br J Cancer, 2015;112(8):1314-25.
      Species: Human
      Sample Type: Whole Blood
    28. MEK Inhibitor PD-0325901 Overcomes Resistance to PI3K/mTOR Inhibitor PF-5212384 and Potentiates Antitumor Effects in Human Head and Neck Squamous Cell Carcinoma.
      Authors: Mohan S, Vander Broek R, Shah S, Eytan D, Pierce M, Carlson S, Coupar J, Zhang J, Cheng H, Chen Z, Van Waes C
      Clin Cancer Res, 2015;21(17):3946-56.
      Species: Human
      Sample Type: Cell Culture Supernates
    29. The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells.
      Authors: Sathanoori R, Sward K, Olde B, Erlinge D
      PLoS ONE, 2015;10(5):e0125111.
      Species: Human
      Sample Type: Cell Culture Supernates
    30. Group B streptococcal infection and activation of human astrocytes.
      Authors: Stoner T, Weston T, Trejo J, Doran K
      PLoS ONE, 2015;10(6):e0128431.
      Species: Human
      Sample Type: Cell Lysates
    31. Effect of Sfrp5 on cytokine release and insulin action in primary human adipocytes and skeletal muscle cells.
      Authors: Carstensen M, Wiza C, Rohrig K, Fahlbusch P, Roden M, Herder C, Ouwens D
      PLoS ONE, 2014;9(1):e85906.
      Species: Human
      Sample Type: Cell Culture Supernates
    32. From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract.
      Authors: Ebeling, Sandra, Naumann, Katrin, Pollok, Simone, Wardecki, Tina, Vidal-Y-Sy, Sabine, Nascimento, Juliana, Boerries, Melanie, Schmidt, Gudula, Brandner, Johanna, Merfort, Irmgard
      PLoS ONE, 2014;9(1):e86147.
      Species: Human
      Sample Type: Cell Culture Supernates
    33. Variable NF-kappaB pathway responses in colon cancer cells treated with chemotherapeutic drugs.
      Authors: Samuel T, Fadlalla K, Gales D, Putcha B, Manne U
      BMC Cancer, 2014;14(0):599.
      Species: Human
      Sample Type: Cell Culture Supernates
    34. Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease.
      Authors: Chana K, Fenwick P, Nicholson A, Barnes P, Donnelly L
      J Allergy Clin Immunol, 2014;133(1):207-16.e1-11.
      Species: Human
      Sample Type: cell culture supernate
    35. Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation.
      Authors: De Stefano D, Villella V, Esposito S, Tosco A, Sepe A, De Gregorio F, Salvadori L, Grassia R, Leone C, De Rosa G, Maiuri M, Pettoello-Mantovani M, Guido S, Bossi A, Zolin A, Venerando A, Pinna L, Mehta A, Bona G, Kroemer G, Maiuri L, Raia V
      Autophagy, 2014;10(11):2053-74.
      Species: Human
      Sample Type: Sputum
    36. Icariin ameliorates cigarette smoke induced inflammatory responses via suppression of NF-kappaB and modulation of GR in vivo and in vitro.
      Authors: Li L, Sun J, Xu C, Zhang H, Wu J, Liu B, Dong J
      PLoS ONE, 2014;9(8):e102345.
      Species: Human
      Sample Type: Cell Culture Supernates
    37. Toll-like receptor 10 is involved in induction of innate immune responses to influenza virus infection.
      Authors: Lee S, Kok K, Jaume M, Cheung T, Yip T, Lai J, Guan Y, Webster R, Jin D, Peiris J
      Proc Natl Acad Sci U S A, 2014;111(10):3793-8.
      Species: Human
      Sample Type: cell supernates
    38. Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy.
      Authors: Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, Schwartz L, Morosi C, Crippa F, Fare E, Nicolai N, Lanocita R, Sava T, Sacco C, Messina C, Ortega C, De Braud F, Salvioni R, Daidone M, Gianni A, Mariani L
      Br J Cancer, 2014;110(1):26-33.
      Species: Human
      Sample Type: Plasma
    39. The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia.
      Authors: Chou C, Lin F, Tsai H, Chang S
      BMC Pulm Med, 2014;14(0):182.
      Species: Human
      Sample Type: BALF
    40. Bacteria induce prolonged PMN survival via a phosphatidylcholine-specific phospholipase C- and protein kinase C-dependent mechanism.
      Authors: Erttmann S, Gekara N, Fallman M
      PLoS ONE, 2014;9(1):e87859.
      Species: Human
      Sample Type: Cell Culture Supernates
    41. Thrombin-induced CCAAT/enhancer-binding protein beta activation and IL-8/CXCL8 expression via MEKK1, ERK, and p90 ribosomal S6 kinase 1 in lung epithelial cells.
      Authors: Lin C, Nai P, Bien M, Yu C, Chen B
      J Immunol, 2014;192(1):338-48.
      Species: Human
      Sample Type: Cell Culture Supernates
    42. Association between visceral fat, IL-8 and endometrial cancer.
      Authors: Ciortea, Razvan, Mihu, Dan, Mihu, Carmen M
      Anticancer Res, 2014;34(1):379-83.
      Species: Human
      Sample Type: Plasma
    43. miR-200c regulates IL8 expression by targeting IKBKB: a potential mediator of inflammation in leiomyoma pathogenesis.
      Authors: Chuang T, Khorram O
      PLoS ONE, 2014;9(4):e95370.
      Species: Human
      Sample Type: Conditioned media
    44. Identification of two forms of TNF tolerance in human monocytes: differential inhibition of NF-kappaB/AP-1- and PP1-associated signaling.
      Authors: Gunther J, Vogt N, Hampel K, Bikker R, Page S, Muller B, Kandemir J, Kracht M, Dittrich-Breiholz O, Huber R, Brand K
      J Immunol, 2014;192(7):3143-55.
      Species: Human
      Sample Type: Cell Culture Supernates
    45. beta-glucan induces reactive oxygen species production in human neutrophils to improve the killing of Candida albicans and Candida glabrata isolates from vulvovaginal candidiasis.
      Authors: Bonfim-Mendonca P, Ratti B, Godoy J, Negri M, Lima N, Fiorini A, Hatanaka E, Consolaro M, de Oliveira Silva S, Svidzinski T
      PLoS ONE, 2014;9(9):e107805.
      Species: Human
      Sample Type: Cell Culture Supernates
    46. Novel antimicrobial peptides that inhibit gram positive bacterial exotoxin synthesis.
      Authors: Merriman J, Nemeth K, Schlievert P
      PLoS ONE, 2014;9(4):e95661.
      Species: Human
      Sample Type: Cell Culture Supernates
    47. PARP12, an interferon-stimulated gene involved in the control of protein translation and inflammation.
      Authors: Welsby I, Hutin D, Gueydan C, Kruys V, Rongvaux A, Leo O
      J Biol Chem, 2014;289(38):26642-57.
      Species: Human
      Sample Type: Cell Culture Supernates
    48. Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells.
      Authors: Smrz D, Bandara G, Beaven M, Metcalfe D, Gilfillan A
      Eur J Immunol, 2013;43(7):1873-82.
      Species: Human
      Sample Type: Cell Culture Supernates
    49. ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth.
      Authors: Moreno A, Soleto I, Garcia-Sanz P, Moreno-Bueno G, Palmero I
      Oncogene, 2013;33(15):1945-53.
      Species: Human
      Sample Type: Cell Culture Supernates
    50. Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor.
      Authors: Suzuki M, Takaishi S, Nagasaki M, Onozawa Y, Iino I, Maeda H, Komai T, Oda T
      J Biol Chem, 2013;288(15):10684-91.
      Species: Human
      Sample Type: Cell Culture Supernates
    51. Species-specific PAMP recognition by TLR2 and evidence for species-restricted interaction with Dectin-1.
      Authors: Willcocks S, Offord V, Seyfert H, Coffey T, Werling D
      J Leukoc Biol, 2013;94(3):449-58.
      Species: Bovine
      Sample Type: cell supernates
    52. Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
      Authors: Cerdeira A, Rajakumar A, Royle C, Lo A, Husain Z, Thadhani R, Sukhatme V, Karumanchi S, Kopcow H
      J Immunol, 2013;190(8):3939-48.
      Species: Human
      Sample Type: Cell Culture Supernates
    53. Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
      Authors: Sawada H, Saito T, Nickel N, Alastalo T, Glotzbach J, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai Y, Perez V, Kim Y, Wang L, Chen P, Spiekerkoetter E, Mitani Y, Gurtner G, Sarnow P, Rabinovitch M
      J Exp Med, 2013;211(2):263-80.
      Species: Human
      Sample Type: Cell Culture Supernates
    54. MAPK-activated protein kinase 2 contributes to Clostridium difficile-associated inflammation.
      Authors: Bobo L, El Feghaly R, Chen Y, Dubberke E, Han Z, Baker A, Li J, Burnham C, Haslam D
      Infect Immun, 2013;81(3):713-22.
      Species: Human
      Sample Type: Fecal
    55. Enterococcus faecalis inhibits superantigen toxic shock syndrome toxin-1-induced interleukin-8 from human vaginal epithelial cells through tetramic acids.
      Authors: Brosnahan A, Merriman J, Salgado-Pabon W, Ford B, Schlievert P
      PLoS ONE, 2013;8(4):e61255.
      Species: Human
      Sample Type: Cell Culture Supernates
    56. Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid.
      Authors: Tzeng, Tsai-Ten, Tsay, Huey-Jen, Chang, Luping, Hsu, Chia-Lin, Lai, Tzu-Hsua, Huang, Fong-Lee, Shiao, Young-Ji
      J Biomed Sci, 2013;20(0):90.
      Species: Human
      Sample Type: Cell Culture Supernates
    57. Homotrimeric macrophage migration inhibitory factor (MIF) drives inflammatory responses in the corneal epithelium by promoting caveolin-rich platform assembly in response to infection.
      Authors: Reidy, Thomas, Rittenberg, Alexande, Dwyer, Markryan, D'Ortona, Samantha, Pier, Gerald, Gadjeva, Mihaela
      J Biol Chem, 2013;288(12):8269-78.
      Species: Human
      Sample Type: Whole Cells
    58. The serine phosphatase SerB of Porphyromonas gingivalis suppresses IL-8 production by dephosphorylation of NF-kappaB RelA/p65.
      Authors: Takeuchi H, Hirano T, Whitmore S, Morisaki I, Amano A, Lamont R
      PLoS Pathog, 2013;9(4):e1003326.
      Species: Human
      Sample Type: Cell Culture Supernates
    59. Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
      Authors: Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbe C, Caillat-Zucman S
      PLoS Pathog., 2012;8(1):e1002486.
      Species: Human
      Sample Type: Cell Culture Supernates
    60. Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses.
      Authors: Andersson M, Lutay N, Hallgren O, Westergren-Thorsson G, Svensson M, Godaly G
      Innate Immun, 2012;18(3):531-40.
      Species: Human
      Sample Type: Cell Culture Supernates
    61. Late SV40 factor (LSF) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP-9).
      Authors: Santhekadur PK, Gredler R, Chen D
      J. Biol. Chem., 2012;287(5):3425-32.
      Species: Human
      Sample Type: Cell Culture Supernates
    62. Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes.
      J. Invest. Dermatol., 2012;132(11):2593-600.
      Species: Human
      Sample Type: Cell Culture Supernates
    63. Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
      Authors: Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK
      J. Immunol., 2012;188(3):1002-10.
      Species: Human
      Sample Type: Cell Culture Supernates
    64. Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury.
      Authors: Quesnel C, Piednoir P, Gelly J, Nardelli L, Garnier M, Lecon V, Lasocki S, Bouadma L, Philip I, Elbim C, Mentre F, Soler P, Crestani B, Dehoux M
      Crit. Care Med., 2012;40(1):21-8.
      Species: Human
      Sample Type: BALF
    65. Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation.
      Authors: Sakitani K, Hirata Y, Hayakawa Y, Serizawa T, Nakata W, Takahashi R, Kinoshita H, Sakamoto K, Nakagawa H, Akanuma M, Yoshida H, Maeda S, Koike K
      Infect Immun, 2012;80(11):3795-803.
      Species: Human
      Sample Type: Cell Lysates
    66. A key role for the endothelium in NOD1 mediated vascular inflammation: comparison to TLR4 responses.
      Authors: Gatheral T, Reed D, Moreno L, Gough P, Votta B, Sehon C, Rickard D, Bertin J, Lim E, Nicholson A, Mitchell J
      PLoS ONE, 2012;7(8):e42386.
      Species: Human
      Sample Type: Cell Culture Supernates
    67. IL-33 promotes the migration and proliferation of circulating fibrocytes from patients with allergen-exacerbated asthma.
      Authors: Bianchetti L, Marini M, Isgro M, Bellini A, Schmidt M, Mattoli S
      Biochem Biophys Res Commun, 2012;426(1):116-21.
      Species: Human
      Sample Type: Cell Culture Supernates
    68. A randomized trial of recombinant human granulocyte-macrophage colony stimulating factor for patients with acute lung injury.
      Authors: Paine R, Standiford TJ, Dechert RE, Moss M, Martin GS, Rosenberg AL, Thannickal VJ, Burnham EL, Brown MB, Hyzy RC
      Crit. Care Med., 2012;40(1):90-7.
      Species: Human
      Sample Type: BALF
    69. Biomarkers for antitumor activity of bevacizumab in gastric cancer models.
      Authors: Yamashita-Kashima Y, Fujimoto-Ouchi K, Yorozu K, Kurasawa M, Yanagisawa M, Yasuno H, Mori K
      BMC Cancer, 2012;12(0):37.
      Species: Human
      Sample Type: Tissue Homogenates
    70. Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1.
      Authors: Schaefers MM, Breshears LM, Anderson MJ, Lin YC, Grill AE, Panyam J, Southern PJ, Schlievert PM, Peterson ML
      PLoS ONE, 2012;7(3):e32813.
      Species: Porcine
      Sample Type: Cell Culture Supernates
    71. Characterization of innate immune signalling receptors in virus-induced acute asthma.
      Authors: Wood LG, Simpson JL, Wark PA, Powell H, Gibson PG
      Clin. Exp. Allergy, 2011;41(5):640-8.
      Species: Human
      Sample Type: Saliva
    72. TLR4 Protein Contributes to Cigarette Smoke-induced Matrix Metalloproteinase-1 (MMP-1) Expression in Chronic Obstructive Pulmonary Disease.
      Authors: Geraghty P, Dabo AJ, D'Armiento J
      J. Biol. Chem., 2011;286(34):30211-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    73. Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells.
      Authors: McGuire TR, Brusnahan SK, Bilek LD, Jackson JD, Kessinger MA, Berger AM, Garvin KL, O'Kane BJ, Tuljapurkar SR, Sharp JG
      Obesity (Silver Spring), 2011;19(11):2130-6.
      Species: Human
      Sample Type: Plasma
    74. Increased expression of matrix metalloproteinase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction.
      Authors: Estrada-Gutierrez G, Cappello RE, Mishra N, Romero R, Strauss JF, Walsh SW
      Am. J. Pathol., 2011;178(1):451-60.
      Species: Human
      Sample Type: Cell Culture Supernates
    75. Curcumin treatment suppresses IKKbeta kinase activity of salivary cells of patients with head and neck cancer: a pilot study.
      Authors: Kim SG, Veena MS, Basak SK, Han E, Tajima T, Gjertson DW, Starr J, Eidelman O, Pollard HB, Srivastava M, Srivatsan ES, Wang MB
      Clin. Cancer Res., 2011;17(18):5953-61.
      Species: Human
      Sample Type: Saliva
    76. Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes.
      Authors: Verma S, Kumar M, Nerurkar VR
      J. Gen. Virol., 2011;92(0):507-15.
      Species: Human
      Sample Type: Cell Culture Supernates
    77. p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype.
      Authors: Freund A, Patil CK, Campisi J
      EMBO J., 2011;30(8):1536-48.
      Species: Human
      Sample Type: Cell Culture Supernates
    78. Role of inflammation and insulin resistance in endothelial progenitor cell dysfunction.
      Authors: Desouza CV, Hamel FG, Bidasee K, O'Connell K
      Diabetes, 2011;60(4):1286-94.
      Species: Human
      Sample Type: Cell Culture Supernates
    79. Opposing roles of IL-17A and IL-25 in the regulation of TSLP production in human nasal epithelial cells.
      Authors: Xu G, Zhang L, Wang DY, Xu R, Liu Z, Han DM, Wang XD, Zuo KJ, Li HB
      Allergy, 2010;65(5):581-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    80. Placental growth factor neutralising antibodies give limited anti-angiogenic effects in an in vitro organotypic angiogenesis model.
      Authors: Brave SR, Eberlein C, Shibuya M, Wedge SR, Barry ST
      Angiogenesis, 2010;13(4):337-47.
      Species: Human
      Sample Type: Cell Culture Supernates
    81. Oxidative stress enhances toll-like receptor 3 response to double-stranded RNA in airway epithelial cells.
      Authors: Koarai A, Sugiura H, Yanagisawa S
      Am. J. Respir. Cell Mol. Biol., 2010;42(6):651-60.
      Species: Human
      Sample Type: Cell Culture Supernates
    82. NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.
      Authors: Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W
      J. Clin. Invest., 2010;120(5):1645-62.
      Species: Human
      Sample Type: Cell Culture Supernates
    83. A phase I trial of bortezomib with temozolomide in patients with advanced melanoma: toxicities, antitumor effects, and modulation of therapeutic targets.
      Authors: Su Y, Amiri KI, Horton LW
      Clin. Cancer Res., 2010;16(1):348-57.
      Species: Human
      Sample Type: Serum
    84. Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients.
      Authors: Glynn SA, Boersma BJ, Dorsey TH, Yi M, Yfantis HG, Ridnour LA, Martin DN, Switzer CH, Hudson RS, Wink DA, Lee DH, Stephens RM, Ambs S
      J. Clin. Invest., 2010;120(11):3843-54.
      Species: Human
      Sample Type: Cell Culture Supernates
    85. Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37.
      Authors: Kai-Larsen Y, Luthje P, Chromek M, Peters V, Wang X, Holm A, Kadas L, Hedlund KO, Johansson J, Chapman MR, Jacobson SH, Romling U, Agerberth B, Brauner A
      PLoS Pathog., 2010;6(0):e1001010.
      Species: Human
      Sample Type: Urine
    86. Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer.
      Authors: Gannon PO, Godin-Ethier J, Hassler M, Delvoye N, Aversa M, Poisson AO, Peant B, Alam Fahmy M, Saad F, Lapointe R, Mes-Masson AM
      PLoS ONE, 2010;5(8):e12107.
      Species: Human
      Sample Type: Cell Culture Supernates
    87. Mannitol challenge for assessment of airway responsiveness, airway inflammation and inflammatory phenotype in asthma.
      Authors: Wood LG, Powell H, Gibson PG
      Clin. Exp. Allergy, 2010;40(2):232-41.
      Species: Human
      Sample Type: Saliva
    88. Discovery of a novel class of targeted kinase inhibitors that blocks protein kinase C signaling and ameliorates retinal vascular leakage in a diabetic rat model.
      Authors: Grant S, Tran P, Zhang Q, Zou A, Dinh D, Jensen J, Zhou S, Kang X, Zachwieja J, Lippincott J, Liu K, Johnson SL, Scales S, Yin C, Nukui S, Stoner C, Prasanna G, Lafontaine J, Wells P, Li H
      Eur. J. Pharmacol., 2010;627(1):16-25.
      Species: Human
      Sample Type: Cell Culture Supernates
    89. IL-33 mediates inflammatory responses in human lung tissue cells.
      Authors: Yagami A, Orihara K, Morita H
      J. Immunol., 2010;185(10):5743-50.
      Species: Human
      Sample Type: Cell Culture Supernates
    90. Maternal country of origin, breast milk characteristics and potential influences on immunity in offspring.
      Authors: Holmlund U, Amoudruz P, Johansson MA, Haileselassie Y, Ongoiba A, Kayentao K, Traore B, Doumbo S, Schollin J, Doumbo O, Montgomery SM, Sverremark-Ekstrom E
      Clin. Exp. Immunol., 2010;162(3):500-9.
      Species: Human
      Sample Type: Milk
    91. Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms.
      Authors: Rydkina E, Turpin LC, Sahni SK
      Infect. Immun., 2010;78(6):2599-606.
      Species: Human
      Sample Type: Cell Culture Supernates
    92. Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells.
      Authors: Tso GH, Law HK, Tu W
      Stem Cells, 2010;28(5):939-54.
      Species: Human
      Sample Type: Cell Culture Supernates
    93. Sensitive plasma protein analysis by microparticle-based proximity ligation assays.
      Authors: Darmanis S, Nong RY, Hammond M, Gu J, Alderborn A, Vanelid J, Siegbahn A, Gustafsdottir S, Ericsson O, Landegren U, Kamali-Moghaddam M
      Mol. Cell Proteomics, 2010;9(2):327-35.
      Species: Human
      Sample Type: Plasma
    94. CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis.
      Authors: Yang G, Rosen DG, Liu G
      Clin. Cancer Res., 2010;16(15):3875-86.
      Species: Human
      Sample Type: Cell Culture Supernates
    95. Macrophage inflammatory protein-1beta induced cell adhesion with increased intracellular reactive oxygen species.
      Authors: Tatara Y, Ohishi M, Yamamoto K, Shiota A, Hayashi N, Iwamoto Y, Takeda M, Takagi T, Katsuya T, Ogihara T, Rakugi H
      J. Mol. Cell. Cardiol., 2009;47(1):104-11.
      Species: Human
      Sample Type: Plasma
    96. The major outer membrane protein of a periodontopathogen induces IFN-beta and IFN-stimulated genes in monocytes via lipid raft and TANK-binding kinase 1/IFN regulatory factor-3.
      Authors: Lee SH, Kim JS, Jun HK
      J. Immunol., 2009;182(9):5823-35.
      Species: Human
      Sample Type: Cell Culture Supernates
    97. The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation.
      Authors: Hardison MT, Galin FS, Calderon CE, Djekic UV, Parker SB, Wille KM, Jackson PL, Oster RA, Young KR, Blalock JE, Gaggar A
      J. Immunol., 2009;182(7):4423-31.
      Species: Human
      Sample Type: BALF
    98. Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism.
      Authors: Semiramoth N, Gleizes A, Turbica I, Sandre C, Gorges R, Kansau I, Servin A, Chollet-Martin S
      J. Leukoc. Biol., 2009;85(2):310-21.
      Species: Human
      Sample Type: Cell Culture Supernates
    99. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
      Authors: Rodier F, Coppe JP, Patil CK, Hoeijmakers WA, Munoz DP, Raza SR, Freund A, Campeau E, Davalos AR, Campisi J
      Nat. Cell Biol., 2009;11(8):973-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    100. Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis.
      Authors: Watanabe H, Kawaguchi M, Fujishima S, Ogura M, Matsukura S, Takeuchi H, Ohba M, Sueki H, Kokubu F, Hizawa N, Adachi M, Huang SK, Iijima M
      J. Invest. Dermatol., 2009;129(3):650-6.
      Species: Human
      Sample Type: Cell Culture Supernates
    101. Crimean Congo hemorrhagic fever virus infects human monocyte-derived dendritic cells.
      Authors: Connolly-Andersen AM, Douagi I, Kraus AA, Mirazimi A
      Virology, 2009;390(2):157-62.
      Species: Human
      Sample Type: Cell Culture Supernates
    102. Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia.
      Authors: Troseid M, Seljeflot I, Hjerkinn EM, Arnesen H
      Diabetes Care, 2009;32(3):486-92.
      Species: Human
      Sample Type: Serum
    103. Dysregulation of stromal derived factor 1/CXCR4 axis in the megakaryocytic lineage in essential thrombocythemia.
      Authors: Salim JP, Goette NP, Lev PR, Chazarreta CD, Heller PG, Alvarez C, Molinas FC, Marta RF
      Br. J. Haematol., 2009;144(1):69-77.
      Species: Human
      Sample Type: Plasma
    104. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis.
      Authors: Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Froland SS, Olofsson PS, Damas JK, Gullestad L, Hansson GK, Oie E, Aukrust P
      Circ. Res., 2009;104(1):60-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    105. Age-dependent mobilization of circulating endothelial progenitor cells in infants and young children undergoing cardiac surgery with cardiopulmonary bypass.
      Authors: Sun Y, Yi D, Wang Y, Zheng R, Sun G, Wang J, Liu Y, Ren J, Wang Y, Zhang S, Gu C, Pei J
      Cytokine, 2009;47(3):206-13.
      Species: Human
      Sample Type: Plasma
    106. Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease.
      Authors: Miller M, Cho JY, Pham A, Ramsdell J, Broide DH
      J. Immunol., 2009;182(1):684-91.
      Species: Human
      Sample Type: Cell Culture Supernates
    107. Soluble TLR2 is present in human amniotic fluid and modulates the intraamniotic inflammatory response to infection.
      Authors: Dulay AT, Buhimschi CS, Zhao G, Oliver EA, Mbele A, Jing S, Buhimschi IA
      J. Immunol., 2009;182(11):7244-53.
      Species: Human
      Sample Type: Amniotic Fluid
    108. MMP dependence of fibroblast contraction and collagen production induced by human mast cell activation in a three-dimensional collagen lattice.
      Authors: Margulis A, Nocka KH, Wood NL, Wolf SF, Goldman SJ, Kasaian MT
      Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(2):L236-47.
      Species: Human
      Sample Type: Cell Culture Supernates
    109. Immunomodulation of nasal epithelial cells by Staphylococcus aureus-derived serine proteases.
      Authors: Rudack C, Sachse F, Albert N, Becker K, von Eiff C
      J. Immunol., 2009;183(11):7592-601.
      Species: Human
      Sample Type: Cell Culture Supernates
    110. Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts.
      Authors: Mizutani K, Sud S, Pienta KJ
      J. Cell. Biochem., 2009;106(4):563-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    111. In vitro neutralization of tumor necrosis factor-alpha during Chlamydia pneumoniae infection impairs dendritic cells maturation/function and increases chlamydial progeny.
      Authors: Njau F, Wittkop U, Rohde M, Haller H, Klos A, Wagner AD
      FEMS Immunol. Med. Microbiol., 2009;55(2):215-25.
      Species: Human
      Sample Type: Cell Culture Supernates
    112. Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease.
      Authors: Smith AM, Rahman FZ, Hayee B, Graham SJ, Marks DJ, Sewell GW, Palmer CD, Wilde J, Foxwell BM, Gloger IS, Sweeting T, Marsh M, Walker AP, Bloom SL, Segal AW
      J. Exp. Med., 2009;206(9):1883-97.
      Species: Human
      Sample Type: Cell Culture Supernates
    113. Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome.
      Authors: Campeau PM, Rafei M, Boivin MN, Sun Y, Grabowski GA, Galipeau J
      Blood, 2009;114(15):3181-90.
      Species: Human
      Sample Type: Cell Culture Supernates
    114. Assessment of cervicovaginal cytokine levels following exposure to microbicide Nisin gel in rabbits.
      Authors: Aranha CC, Gupta SM, Reddy KV
      Cytokine, 2008;43(1):63-70.
      Species: Rabbit
      Sample Type: Cell Culture Supernates
    115. Serum and urine levels of interleukin-8 in patients with non-Hodgkin's lymphoma.
      Authors: Lee HL, Eom HS, Yun T, Kim HJ, Park WS, Nam BH, Moon-Woo S, Lee DH, Kong SY
      Cytokine, 2008;43(1):71-5.
      Species: Human
      Sample Type: Serum
    116. In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22.
      Authors: Olsnes AM, Ryningen A, Ersvaer E, Bruserud Ø
      J. Interferon Cytokine Res., 2008;28(5):297-310.
      Species: Human
      Sample Type: Cell Culture Supernates
    117. Particulate matter in cigarette smoke alters iron homeostasis to produce a biological effect.
      Authors: Ghio AJ, Hilborn ED, Stonehuerner JG, Dailey LA, Carter JD, Richards JH, Crissman KM, Foronjy RF, Uyeminami DL, Pinkerton KE
      Am. J. Respir. Crit. Care Med., 2008;178(11):1130-8.
      Species: Human
      Sample Type: BALF
    118. IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis.
      Authors: Skov L, Beurskens FJ, Zachariae CO, Reitamo S, Teeling J, Satijn D, Knudsen KM, Boot EP, Hudson D, Baadsgaard O, Parren PW, van de Winkel JG
      J. Immunol., 2008;181(1):669-79.
      Species: Human
      Sample Type: palmoplantar pustulosis wash fluid
    119. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils.
      Authors: Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H
      J. Allergy Clin. Immunol., 2008;121(6):1484-90.
      Species: Human
      Sample Type: Cell Culture Supernates
    120. cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo.
      Authors: Siddappa R, Martens A, Doorn J, Leusink A, Olivo C, Licht R, van Rijn L, Gaspar C, Fodde R, Janssen F, van Blitterswijk C, de Boer J
      Proc. Natl. Acad. Sci. U.S.A., 2008;105(20):7281-6.
      Species: Human
      Sample Type: Cell Culture Supernates
    121. Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
      Authors: Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
      J. Neuroimmunol., 2008;199(1):35-45.
      Species: Human
      Sample Type: Cell Culture Supernates
    122. Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway.
      Authors: Bergin DA, Greene CM, Sterchi EE, Kenna C, Geraghty P, Belaaouaj A, Taggart CC, O'Neill SJ, McElvaney NG
      J. Biol. Chem., 2008;283(46):31736-44.
      Species: Human
      Sample Type: Cell Culture Supernates
    123. NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population.
      Authors: Zhang Y, Lin M, Zhang S, Wang Z, Jiang L, Shen J, Bai J, Gao F, Zhou M, Chen Q
      Cytokine, 2008;41(2):144-9.
      Species: Human
      Sample Type: Serum
    124. MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells.
      Authors: Le Quement C, Guenon I, Gillon JY, Lagente V, Boichot E
      Am. J. Physiol. Lung Cell Mol. Physiol., 2008;294(6):L1076-84.
      Species: Human
      Sample Type: Cell Culture Supernates
    125. High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins.
      Authors: Smith C, Halvorsen B, Otterdal K, Waehre T, Yndestad A, Fevang B, Sandberg WJ, Breland UM, Froland SS, Oie E, Gullestad L, Damas JK, Aukrust P
      Cardiovasc. Res., 2008;79(1):195-203.
      Species: Human
      Sample Type: Cell Culture Supernates
    126. Validation of assays for inflammatory mediators in exhaled breath condensate.
      Authors: Bayley DL, Abusriwil H, Ahmad A, Stockley RA
      Eur. Respir. J., 2008;31(5):943-8.
      Species: Human
      Sample Type: Sputum
    127. Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma.
      Authors: Hothersall EJ, Chaudhuri R, McSharry C, Donnelly I, Lafferty J, McMahon AD, Weir CJ, Meiklejohn J, Sattar N, McInnes I, Wood S, Thomson NC
      Thorax, 2008;63(12):1070-5.
      Species: Human
      Sample Type: Serum
    128. Co-occurrence of IgA antibodies against ethanol metabolites and tissue transglutaminase in alcohol consumers: correlation with proinflammatory cytokines and markers of fibrogenesis.
      Authors: Koivisto H, Hietala J, Anttila P, Niemela O
      Dig. Dis. Sci., 2007;53(2):500-5.
      Species: Human
      Sample Type: Serum
    129. Tissue engineering for full-thickness burns: a dermal substitute from bench to bedside.
      Authors: Kellouche S, Martin C, Korb G, Rezzonico R, Bouard D, Benbunan M, Dubertret L, Soler C, Legrand C, Dosquet C
      Biochem. Biophys. Res. Commun., 2007;363(3):472-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    130. Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis.
      Authors: Bae E, Kim WJ, Kang YM, Suk K, Koh EM, Cha HS, Ahn KS, Huh TL, Lee WH
      Clin. Exp. Immunol., 2007;148(3):410-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    131. The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis.
      Authors: Colla S, Tagliaferri S, Morandi F, Lunghi P, Donofrio G, Martorana D, Mancini C, Lazzaretti M, Mazzera L, Ravanetti L, Bonomini S, Ferrari L, Miranda C, Ladetto M, Neri TM, Neri A, Greco A, Mangoni M, Bonati A, Rizzoli V, Giuliani N
      Blood, 2007;110(13):4464-75.
      Species: Human
      Sample Type: Plasma
    132. The influence of anger expression on wound healing.
      Authors: Gouin JP, Kiecolt-Glaser JK, Malarkey WB, Glaser R
      Brain Behav. Immun., 2007;22(5):699-708.
      Species: Human
      Sample Type: Wound Secretion
    133. Th1/Th2 cytokines reciprocally regulate in vitro pulmonary angiogenesis via CXC chemokine synthesis.
      Authors: Matsuda A, Fukuda S, Matsumoto K, Saito H
      Am. J. Respir. Cell Mol. Biol., 2007;38(2):168-75.
      Species: Human
      Sample Type: Cell Culture Supernates
    134. Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro.
      Authors: Neuhoff S, Moers J, Rieks M, Grunwald T, Jensen A, Dermietzel R, Meier C
      Exp. Hematol., 2007;35(7):1119-31.
      Species: Human
      Sample Type: Cell Culture Supernates
    135. Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.
      Authors: Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A
      Proc. Natl. Acad. Sci. U.S.A., 2007;104(7):2319-24.
      Species: Human
      Sample Type: Cell Culture Supernates
    136. Dehydroepiandrosterone inhibits the TNF-alpha-induced inflammatory response in human umbilical vein endothelial cells.
      Authors: Gutierrez G, Mendoza C, Zapata E, Montiel A, Reyes E, Montano LF, Lopez-Marure R
      Atherosclerosis, 2007;190(1):90-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    137. Lung injury after ozone exposure is iron dependent.
      Authors: Ghio AJ, Turi JL, Madden MC, Dailey LA, Richards JD, Stonehuerner JG, Morgan DL, Singleton S, Garrick LM, Garrick MD
      Am. J. Physiol. Lung Cell Mol. Physiol., 2007;292(1):L134-43.
      Species: Human
      Sample Type: Cell Culture Supernates
    138. IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation.
      Authors: Dame TM, Orenzoff BL, Palmer LE, Furie MB
      J. Immunol., 2007;178(2):1172-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    139. Cytokine profiling in human colostrum and milk by protein array.
      Authors: Kverka M, Burianova J, Lodinova-Zadnikova R, Kocourkova I, Cinova J, Tuckova L, Tlaskalova-Hogenova H
      Clin. Chem., 2007;53(5):955-62.
      Species: Human
      Sample Type: Milk
    140. Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke.
      Authors: Mian MF, Lauzon NM, Stampfli MR, Mossman KL, Ashkar AA
      J. Leukoc. Biol., 2007;83(3):774-84.
      Species: Human
      Sample Type: Cell Culture Supernates
    141. MAPK pathway mediates EGR-1-HSP70-dependent cigarette smoke-induced chemokine production.
      Authors: Li CJ, Ning W, Matthay MA, Feghali-Bostwick CA, Choi AM
      Am. J. Physiol. Lung Cell Mol. Physiol., 2007;292(5):L1297-303.
      Species: Human
      Sample Type: Cell Culture Supernates
    142. Innate immune activation in neutrophilic asthma and bronchiectasis.
      Authors: Simpson JL, Grissell TV, Douwes J, Scott RJ, Boyle MJ, Gibson PG
      Thorax, 2007;62(3):211-8.
      Species: Human
      Sample Type: Sputum
    143. 1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis.
      Authors: Vidyarani M, Selvaraj P, Jawahar MS, Narayanan PR
      Cytokine, 2007;40(2):128-34.
      Species: Human
      Sample Type: Cell Culture Supernates
    144. Securinine, a GABAA receptor antagonist, enhances macrophage clearance of phase II C. burnetii: comparison with TLR agonists.
      Authors: Lubick K, Radke M, Jutila M
      J. Leukoc. Biol., 2007;82(5):1062-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    145. Clarithromycin targets neutrophilic airway inflammation in refractory asthma.
      Authors: Simpson JL, Powell H, Boyle MJ, Scott RJ, Gibson PG
      Am. J. Respir. Crit. Care Med., 2007;177(2):148-55.
      Species: Human
      Sample Type: Sputum
    146. Specificity of immunomodulator secretion in urinary samples in response to infection by alpha-hemolysin and CNF1 bearing uropathogenic Escherichia coli.
      Authors: Real JM, Munro P, Buisson-Touati C, Lemichez E, Boquet P, Landraud L
      Cytokine, 2007;37(1):22-5.
      Species: Human
      Sample Type: Urine
    147. Role of interleukin-8 and growth-regulated oncogene-alpha in the chemotactic migration of all-trans retinoic acid-treated promyelocytic leukemic cells toward alveolar epithelial cells.
      Authors: Tsai WH, Hsu HC, Lin CC, Ho CK, Kou YR
      Crit. Care Med., 2007;35(3):879-85.
      Species: Human
      Sample Type: Cell Culture Supernates
    148. Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation.
      Authors: Coupel S, Moreau A, Hamidou M, Horejsi V, Soulillou JP, Charreau B
      Blood, 2007;109(7):2806-14.
      Species: Human
      Sample Type: Serum
    149. Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection.
      Authors: Zalevsky J, Secher T, Ezhevsky SA, Janot L, Steed PM, O'Brien C, Eivazi A, Kung J, Nguyen DH, Doberstein SK, Erard F, Ryffel B, Szymkowski DE
      J. Immunol., 2007;179(3):1872-83.
      Species: Human
      Sample Type: Cell Culture Supernates
    150. Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.
      Authors: Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, Repici A, Arena V, Malesci A, Panes J, Grinnell BW, Danese S
      J. Clin. Invest., 2007;117(7):1951-60.
      Species: Human
      Sample Type: Cell Culture Supernates
    151. Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema.
      Authors: Miller M, Ramsdell J, Friedman PJ, Cho JY, Renvall M, Broide DH
      J. Allergy Clin. Immunol., 2007;120(5):1118-25.
      Species: Human
      Sample Type: BALF
    152. Cooperative effects of rhinovirus and TNF-{alpha} on airway epithelial cell chemokine expression.
      Authors: Newcomb DC, Sajjan US, Nagarkar DR, Goldsmith AM, Bentley JK, Hershenson MB
      Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(4):L1021-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    153. Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells.
      Authors: Lin YL, Liang YC, Chiang BL
      J. Leukoc. Biol., 2007;82(6):1473-80.
      Species: Human
      Sample Type: Cell Culture Supernates
    154. L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion.
      Authors: Abe Y, Fornage M, Yang CY, Bui-Thanh NA, Wise V, Chen HH, Rangaraj G, Ballantyne CM
      Atherosclerosis, 2007;192(1):56-66.
      Species: Human
      Sample Type: Cell Culture Supernates
    155. In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury.
      Authors: Perkins GD, Nathani N, McAuley DF, Gao F, Thickett DR
      Thorax, 2007;62(1):36-42.
      Species: Human
      Sample Type: BALF
    156. Different angiogenic activity in pulmonary sarcoidosis and idiopathic pulmonary fibrosis.
      Authors: Antoniou KM, Tzouvelekis A, Alexandrakis MG, Sfiridaki K, Tsiligianni I, Rachiotis G, Tzanakis N, Bouros D, Milic-Emili J, Siafakas NM
      Chest, 2006;130(4):982-8.
      Species: Human
      Sample Type: BALF
    157. Changes in immune and glial markers in the CSF of patients with Complex Regional Pain Syndrome.
      Authors: Alexander GM, Perreault MJ, Reichenberger ER, Schwartzman RJ
      Brain Behav. Immun., 2006;21(5):668-76.
      Species: Human
      Sample Type: CSF
    158. Effect of interactions between lower airway bacterial and rhinoviral infection in exacerbations of COPD.
      Authors: Wilkinson TM, Hurst JR, Perera WR, Wilks M, Donaldson GC, Wedzicha JA
      Chest, 2006;129(2):317-24.
      Species: Human
      Sample Type: Saliva
    159. Urine cytokines profile in renal transplant patients with asymptomatic bacteriuria.
      Authors: Ciszek M, Paczek L, Bartlomiejczyk I, Mucha K
      Transplantation, 2006;81(12):1653-7.
      Species: Human
      Sample Type: Urine
    160. C-reactive protein and vascular cell adhesion molecule-1 as markers of severity in sickle cell disease.
      Authors: Makis AC, Hatzimichael EC, Stebbing J, Bourantas KL
      Arch. Intern. Med., 2006;166(3):366-8.
      Species: Human
      Sample Type: Plasma
    161. The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes.
      Authors: Magne D, Palmer G, Barton JL, Mezin F, Talabot-Ayer D, Bas S, Duffy T, Noger M, Guerne PA, Nicklin MJ, Gabay C
      Arthritis Res. Ther., 2006;8(3):R80.
      Species: Human
      Sample Type: Cell Culture Supernates
    162. Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities.
      Authors: Pang L, Nie M, Corbett L, Sutcliffe A, Knox AJ
      J. Immunol., 2006;176(6):3788-95.
      Species: Human
      Sample Type: Cell Culture Supernates
    163. Respiratory syncytial virus, airway inflammation, and FEV1 decline in patients with chronic obstructive pulmonary disease.
      Authors: Wilkinson TM, Donaldson GC, Johnston SL, Openshaw PJ, Wedzicha JA
      Am. J. Respir. Crit. Care Med., 2006;173(8):871-6.
      Species: Human
      Sample Type: Sputum
    164. Glycerol monolaurate inhibits the effects of Gram-positive select agents on eukaryotic cells.
      Authors: Peterson ML, Schlievert PM
      Biochemistry, 2006;45(7):2387-97.
      Species: Human
      Sample Type: Cell Culture Supernates
    165. Serum and urine levels of interleukin-6 and interleukin-8 in children with acute pyelonephritis.
      Authors: Sheu JN, Chen MC, Lue KH, Cheng SL, Lee IC, Chen SM, Tsay GJ
      Cytokine, 2006;36(5):276-82.
      Species: Human
      Sample Type: Serum
    166. Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation.
      Authors: Smith C, Damas JK, Otterdal K, ØIe E, Sandberg WJ, Yndestad A, Waehre T, Scholz H, Endresen K, Olofsson PS, Halvorsen B, Gullestad L, Froland SS, Hansson GK, Aukrust P
      J. Am. Coll. Cardiol., 2006;48(8):1591-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    167. Functional analysis of the chemokine receptor CCR3 on airway epithelial cells.
      Authors: Beck LA, Tancowny B, Brummet ME, Asaki SY, Curry SL, Penno MB, Foster M, Bahl A, Stellato C
      J. Immunol., 2006;177(5):3344-54.
      Species: Human
      Sample Type: Cell Culture Supernates
    168. Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways.
      Authors: Wang ZY, Yang D, Chen Q, Leifer CA, Segal DM, Su SB, Caspi RR, Howard ZO, Oppenheim JJ
      Exp. Hematol., 2006;34(8):1115-24.
      Species: Human
      Sample Type: Cell Culture Supernates
    169. Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes.
      Authors: Otterdal K, Smith C, Oie E, Pedersen TM, Yndestad A, Stang E, Endresen K, Solum NO, Aukrust P, Damas JK
      Blood, 2006;108(3):928-35.
      Species: Human
      Sample Type: Whole Cells
    170. Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans.
      Authors: Behndig AF, Mudway IS, Brown JL, Stenfors N, Helleday R, Duggan ST, Wilson SJ, Boman C, Cassee FR, Frew AJ, Kelly FJ, Sandstrom T, Blomberg A
      Eur. Respir. J., 2006;27(2):359-65.
    171. High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
      Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
      Cancer Res., 2006;66(8):4198-207.
      Species: Human
      Sample Type: Cell Culture Supernates
    172. Cimetidine does not prevent lung injury in newborn premature infants.
      Authors: Cotton RB, Hazinski TA, Morrow JD, Roberts LJ, Zeldin DC, Lindstrom DP, Lappalainen U, Law AB, Steele S
      Pediatr. Res., 2006;59(6):795-800.
      Species: Human
      Sample Type: Tracheal Lavage
    173. Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis.
      Authors: Hsu YH, Li HH, Hsieh MY, Liu MF, Huang KY, Chin LS, Chen PC, Cheng HH, Chang MS
      Arthritis Rheum., 2006;54(9):2722-33.
      Species: Human
      Sample Type: Cell Culture Supernates
    174. Nasal inflammation and personal exposure to fine particles PM2.5 in asthmatic children.
      Authors: Nikasinovic L, Just J, Sahraoui F, Seta N, Grimfeld A, Momas I
      J. Allergy Clin. Immunol., 2006;117(6):1382-8.
      Species: Human
      Sample Type: nasal lavage
    175. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.
      Authors: Vergne-Salle&lt;/LastName&gt;&lt;F P&lt;/Initial, Vergne-Salle P, Leger DY, Bertin P, Treves R, Beneytout JL, Liagre B
      Cytokine, 2005;31(5):335-48.
      Species: Human
      Sample Type: Cell Culture Supernates
    176. Airway inflammation during stable and acutely exacerbated chronic obstructive pulmonary disease.
      Authors: Fujimoto K, Yasuo M, Urushibata K, Hanaoka M, Koizumi T, Kubo K
      Eur. Respir. J., 2005;25(4):640-6.
      Species: Human
      Sample Type: Sputum
    177. Induced sputum matrix metalloproteinase-9 correlates with lung function and airway inflammation in children with cystic fibrosis.
      Authors: Sagel SD, Kapsner RK, Osberg I
      Pediatr. Pulmonol., 2005;39(3):224-32.
      Species: Human
      Sample Type: Sputum
    178. Experimental heatstroke in baboon: analysis of the systemic inflammatory response.
      Authors: Bouchama A, Ollivier V, Roberts G, Al Mohanna F, de Prost D, Eldali A, Saussereau E, El-Sayed R, Chollet-Martin S
      Shock, 2005;24(4):332-5.
      Species: Primate- Papio hamadryas (Hamadyras Baboon)
      Sample Type: Plasma
    179. Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis.
      Authors: Trevino JG, Summy JM, Gray MJ, Nilsson MB, Lesslie DP, Baker CH, Gallick GE
      Cancer Res., 2005;65(16):7214-22.
      Species: Human
      Sample Type: Cell Culture Supernates
    180. Application of autologous hematopoietic cell therapy to a nonhuman primate model of heterogeneous high-dose irradiation.
      Authors: Bertho JM, Prat M, Frick J, Demarquay C, Gaugler MH, Dudoignon N, Clairand I, Chapel A, Gorin NC, Thierry D, Gourmelon P
      Radiat. Res., 2005;163(5):557-70.
      Species: Primate- Macaca fascicularis (Cynomolgus/Crab-eating Monkey)
      Sample Type: Plasma
    181. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis.
      Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H
      J. Immunol., 2005;175(9):6177-89.
      Species: Human
      Sample Type: Cell Culture Supernates
    182. Relationship between cytokines and the embryotoxicity of hydrosalpingeal fluid.
      Authors: Bedaiwy MA, Falcone T, Goldberg JM, Attaran M, Sharma R, Miller K, Nelson DR, Agarwal A
      J. Assist. Reprod. Genet., 2005;22(4):161-5.
      Species: Human
      Sample Type: Hypersalpingeal fluid (HSF)
    183. Secretory IgA induces antigen-independent eosinophil survival and cytokine production without inducing effector functions.
      Authors: Bartemes KR, Cooper KM, Drain KL, Kita H
      J. Allergy Clin. Immunol., 2005;116(4):827-35.
      Species: Human
      Sample Type: Cell Culture Supernates
    184. Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure.
      Authors: Roos-Engstrand E, Wallin A, Bucht A, Pourazar J, Sandstrom T, Blomberg A
      Eur. Respir. J., 2005;25(5):797-803.
    185. Relationships between allergic inflammation and nasal airflow in children with seasonal allergic rhinitis.
      Authors: Ciprandi G, Tosca MA, Marseglia GL, Klersy C
      Ann. Allergy Asthma Immunol., 2005;94(2):258-61.
      Species: Human
      Sample Type: nasal lavage
    186. Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma.
      Authors: Simpson JL, Scott RJ, Boyle MJ, Gibson PG
      Am. J. Respir. Crit. Care Med., 2005;172(5):559-65.
      Species: Human
      Sample Type: Sputum
    187. Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis.
      Authors: Ren Y, Lin CL, Li Z, Chen XY, Huang X, Lui V, Nicholls J, Lan HY, Tam PK
      Histopathology, 2005;46(6):659-67.
      Species: Human
      Sample Type: Cell Culture Supernates
    188. Interleukin-6 and interleukin-8 in cervical and amniotic fluid: relationship to microbial invasion of the chorioamniotic membranes.
      Authors: Jacobsson B, Mattsby-Baltzer I, Hagberg H
      BJOG, 2005;112(6):719-24.
      Species: Human
      Sample Type: Cervical Fluid
    189. CXC-chemokine stimulation of neutrophils correlates with plasma levels of myeloperoxidase and lactoferrin and contributes to clinical outcome after pediatric cardiac surgery.
      Authors: Gessler P, Pretre R, Hohl V, Rousson V, Fischer J, Dahinden C
      Shock, 2004;22(6):513-20.
      Species: Human
      Sample Type: Plasma
    190. Effect of ozone exposure on airway responses to inhaled allergen in asthmatic subjects.
      Authors: Chen LL, Tager IB, Peden DB, Christian DL, Ferrando RE, Welch BS, Balmes JR
      Chest, 2004;125(6):2328-35.
      Species: Human
      Sample Type: Airway Lavage
    191. Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis.
      Authors: Tramontini N, Huber C, Liu-Bryan R, Terkeltaub RA, Kilgore KS
      Arthritis Rheum., 2004;50(8):2633-9.
      Species: Rabbit
      Sample Type: Synovial Fluid
    192. Influence of eicosapentaenoic acid, an omega-3 fatty acid, on ultraviolet-B generation of prostaglandin-E2 and proinflammatory cytokines interleukin-1 beta, tumor necrosis factor-alpha, interleukin-6 and interleukin-8 in human skin in vivo.
      Authors: Shahbakhti H, Watson RE, Azurdia RM, Ferreira CZ, Garmyn M, Rhodes LE
      Photochem. Photobiol., 2004;80(2):231-5.
      Species: Human
      Sample Type: Plasma
    193. Multiplex bead array assays for detection of soluble cytokines: comparisons of sensitivity and quantitative values among kits from multiple manufacturers.
      Authors: Khan SS, Smith MS, Reda D, Suffredini AF, McCoy JP
      Cytometry B Clin Cytom, 2004;61(1):35-9.
      Species: Human
      Sample Type: Serum
    194. Reduced inspiratory flow attenuates IL-8 release and MAPK activation of lung overstretch.
      Authors: Kotani M, Kotani T, Li Z, Silbajoris R, Piantadosi CA, Huang YC
      Eur. Respir. J., 2004;24(2):238-46.
      Species: Rabbit
      Sample Type: Tissue Homogenates
    195. Normal nasal mucociliary clearance in CF children: evidence against a CFTR-related defect.
      Authors: McShane D, Davies JC, Wodehouse T, Bush A, Geddes D, Alton EW
      Eur. Respir. J., 2004;24(1):95-100.
      Species: Human
      Sample Type: nasal lavage
    196. High concentrations of circulating macrophage migration inhibitory factor in patients with severe blunt trauma: Is serum macrophage migration inhibitory factor concentration a valuable prognostic factor?
      Authors: Chuang CC, Hung CJ, Tsai MC, Chuang YC
      Crit. Care Med., 2004;32(3):734-9.
      Species: Human
      Sample Type: Serum
    197. Bronchiectasis, exacerbation indices, and inflammation in chronic obstructive pulmonary disease.
      Authors: Patel IS, Vlahos I, Wilkinson TM, Lloyd-Owen SJ, Donaldson GC, Wilks M, Reznek RH, Wedzicha JA
      Am. J. Respir. Crit. Care Med., 2004;170(4):400-7.
      Species: Human
      Sample Type: Sputum
    198. Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury.
      Authors: Hayakata T, Shiozaki T, Tasaki O, Ikegawa H, Inoue Y, Toshiyuki F, Hosotubo H, Kieko F, Yamashita T, Tanaka H, Shimazu T, Sugimoto H
      Shock, 2004;22(2):102-7.
      Species: Human
      Sample Type: Serum
    199. Hepatocyte growth factor in polymorphonuclear leukocytes is increased in patients with systemic inflammatory response syndrome.
      Authors: Matsushima A, Ogura H, Koh T, Fujita K, Yoshiya K, Sumi Y, Hosotsubo H, Kuwagata Y, Tanaka H, Shimazu T, Sugimoto H
      J Trauma, 2004;56(2):259-64.
      Species: Human
      Sample Type: Plasma
    200. Guiding the vaginal microbicide trials with biomarkers of inflammation.
      Authors: Fichorova RN
      J. Acquir. Immune Defic. Syndr., 2004;37(0):S184-93.
      Species: Human
      Sample Type: cervicovaginal lavage
    201. Estrogen enhances angiogenesis through a pathway involving platelet-activating factor-mediated nuclear factor-kappaB activation.
      Authors: Seo KH, Lee HS, Jung B, Ko HM, Choi JH, Park SJ, Choi IH, Lee HK, Im SY
      Cancer Res., 2004;64(18):6482-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    202. The effect of respiratory synctial virus on chemokine release by differentiated airway epithelium.
      Authors: Mellow TE, Murphy PC, Carson JL, Noah TL, Zhang L, Pickles RJ
      Exp. Lung Res., 2004;30(1):43-57.
      Species: Human
      Sample Type: Cell Culture Supernates
    203. Interleukin-8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor-alpha and interleukin-1 beta.
      Authors: Park JS, Kim YS, Jee YK, Myong NH, Lee KY
      Scand. J. Immunol., 2003;57(5):463-9.
      Species: Human
      Sample Type: Pleural Effusion
    204. Spontaneous circulation of myeloid-lymphoid-initiating cells and SCID-repopulating cells in sickle cell crisis.
      Authors: Lamming CE, Augustin L, Blackstad M, Lund TC, Hebbel RP, Verfaillie CM
      J. Clin. Invest., 2003;111(6):811-9.
      Species: Human
      Sample Type: Serum
    205. Regulation of the interleukin-5 receptor alpha-subunit on peripheral blood eosinophils from healthy subjects.
      Authors: Hellman C, Hallden G, Hylander B, Lundahl J
      Clin. Exp. Immunol., 2003;131(1):75-81.
      Species: Human
      Sample Type: Peritoneal Fluid
    206. Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection.
      Authors: Geisbert TW, Hensley LE, Larsen T, Young HA, Reed DS, Geisbert JB, Scott DP, Kagan E, Jahrling PB, Davis KJ
      Am. J. Pathol., 2003;163(6):2347-70.
      Species: Primate - Macaca fascicularis (Crab-eating or Cynomolgus macaque)
      Sample Type: Serum
    207. Increased levels of LPS-binding protein in bovine blood and milk following bacterial lipopolysaccharide challenge.
      Authors: Bannerman DD, Paape MJ, Hare WR, Sohn EJ
      J. Dairy Sci., 2003;86(10):3128-37.
      Species: Bovine
      Sample Type: Milk
    208. ELR+ CXC chemokines in human milk.
      Authors: Maheshwari A, Christensen RD, Calhoun DA
      Cytokine, 2003;24(3):91-102.
      Species: Human
      Sample Type: Serum
    209. Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma.
      Authors: Doubrovina ES, Doubrovin MM, Vider E, Sisson RB, O&amp;amp;apos;Reilly RJ, Dupont B, Vyas YM
      J. Immunol., 2003;171(12):6891-9.
      Species: Human
      Sample Type: Serum
    210. Expression of functional CCR and CXCR chemokine receptors in podocytes.
      Authors: Huber TB, Reinhardt HC, Exner M, Burger JA, Kerjaschki D, Saleem MA, Pavenstadt H
      J. Immunol., 2002;168(12):6244-52.
      Species: Human
      Sample Type: Cell Culture Supernates
    211. Local immunostimulation induced by intravesical administration of autologous interferon-gamma-activated macrophages in patients with superficial bladder cancer.
      Authors: Pages F, Lebel-Binay S, Vieillefond A, Deneux L, Cambillau M, Soubrane O, Debre B, Tardy D, Lemonne JL, Abastado JP, Fridman WH, Thiounn N
      Clin. Exp. Immunol., 2002;127(2):303-9.
      Species: Human
      Sample Type: Urine
    212. Embryotoxicity of peritoneal fluid in women with endometriosis. Its relation with cytokines and lymphocyte populations.
      Authors: Gomez-Torres MJ, Acien P, Campos A, Velasco I
      Hum. Reprod., 2002;17(3):777-81.
      Species: Human
      Sample Type: Peritoneal Fluid
    213. Compositional difference in middle ear effusion: mucous versus serous.
      Authors: Chung MH, Choi JY, Lee WS, Kim HN, Yoon JH
      Laryngoscope, 2002;112(1):152-5.
      Species: Human
      Sample Type: middle ear effusion
    214. Cytokine pattern in blister fluid and sera of patients with pemphigus.
      Authors: Baroni A, Perfetto B, Ruocco E, Greco R, Criscuolo D, Ruocco V
      Dermatology (Basel), 2002;205(2):116-21.
      Species: Human
      Sample Type: blister fluid
    215. Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells.
      Authors: Messmer D, Jacque JM, Santisteban C, Bristow C, Han SY, Villamide-Herrera L, Mehlhop E, Marx PA, Steinman RM, Gettie A, Pope M
      J. Immunol., 2002;169(8):4172-82.
      Species: Human
      Sample Type: Cell Culture Supernates
    216. Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gamma delta T lymphocytes.
      Authors: D&amp;amp;apos;Ambrosio D
      Eur. J. Immunol., 2002;32(10):2934-43.
      Species: Human
      Sample Type: Cell Culture Supernates
    217. Detection of fractalkine in human seminal plasma and its role in infertile patients.
      Authors: Zhang Q, Shimoya K, Ohta Y, Chin R, Tenma K, Isaka S, Nakamura H, Koyama M, Azuma C, Murata Y
      Hum. Reprod., 2002;17(6):1560-4.
      Species: Human
      Sample Type: seminal plasma
    218. Chlamydia pneumoniae immunoglobulin A reactivation and airway inflammation in acute asthma.
      Authors: Wark PA, Johnston SL, Simpson JL, Hensley MJ, Gibson PG
      Eur. Respir. J., 2002;20(4):834-40.
      Species: Human
      Sample Type: Sputum
    219. Airway neutrophil inflammation in nonasthmatic patients with food allergy.
      Authors: Wallaert B, Gosset P, Lamblin C, Garcia G, Perez T, Tonnel AB
      Allergy, 2002;57(5):405-10.
      Species: Human
      Sample Type: Saliva
    220. Relationship of changes in interleukin-8 levels and granulocyte elastase activity in gingival crevicular fluid to subgingival periodontopathogens following non-surgical periodontal therapy in subjects with chronic periodontitis.
      Authors: Jin LJ, Leung WK, Corbet EF, Soder B
      J. Clin. Periodontol., 2002;29(7):604-14.
      Species: Human
      Sample Type: Gingival Crevicular Fluid (GCF)
    221. Relationship between airway inflammation and the frequency of exacerbations in patients with smoking related COPD.
      Authors: Gompertz S, Bayley DL, Hill SL, Stockley RA
      Thorax, 2001;56(1):36-41.
      Species: Human
      Sample Type: Saliva
    222. Proinflammatory cytokines increase in sepsis after anti-adhesion molecule therapy.
      Authors: Welty-Wolf KE, Carraway MS, Ghio A, Kantrow SP, Huang YC, Piantadosi CA
      Shock, 2000;13(5):404-9.
      Species: Primate- Papio cynocephalus (Baboon)
      Sample Type: Serum
    223. Luminal neutrophil migration in ileoanal pouches studied by whole gut lavage.
      Authors: Evgenikos NL, Bartolo DC, Hamer-Hodges DW, Ghosh S
      Eur J Gastroenterol Hepatol, 2000;12(5):553-7.
      Species: Human
      Sample Type: gut lavage fluid
    224. Angiogenic balance in human melanoma: expression of VEGF, bFGF, IL-8, PDGF and angiostatin in relation to vascular density of xenografts in vivo.
      Authors: Westphal JR, Van't Hullenaar R, Peek R, Willems RW, Crickard K, Crickard U, Askaa J, Clemmensen I, Ruiter DJ, De Waal RM
      Int. J. Cancer, 2000;86(6):768-76.
      Species: Human
      Sample Type: Cell Culture Supernates
    225. Functional genomic analysis in arthritis-affected cartilage: yin-yang regulation of inflammatory mediators by alpha 5 beta 1 and alpha V beta 3 integrins.
      Authors: Attur MG, Dave MN, Clancy RM, Patel IR, Abramson SB, Amin AR
      J. Immunol., 2000;164(5):2684-91.
      Species: Human
      Sample Type: Cell Culture Supernates
    226. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia.
      Authors: Yates SL, Burgess LH, Kocsis-Angle J, Antal JM, Dority MD, Embury PB, Piotrkowski AM, Brunden KR
      J. Neurochem., 2000;74(3):1017-25.
      Species: Human
      Sample Type: Cell Culture Supernates
    227. Complement fragment C5a and inflammatory cytokines in neutrophil recruitment during intramammary infection with Escherichia coli.
      Authors: Shuster DE, Kehrli ME, Rainard P, Paape M
      Infect. Immun., 1997;65(8):3286-92.
      Species: Bovine
      Sample Type: Serum
    228. Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques.
      Authors: Lehner T, Wang Y, Cranage M, Bergmeier LA, Mitchell E, Tao L, Hall G, Dennis M, Cook N, Brookes R, Klavinskis L, Jones I, Doyle C, Ward R
      Nat. Med., 1996;2(7):767-75.
      Species: Primate - Macaca mulatta (Rhesus monkey)
      Sample Type: Cell Culture Supernates
    229. High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFkappaB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts.
      Authors: Rudisch A, Dewhurst M, Horga L, Kramer N, Harrer N, Dong M, van der Kuip H, Wernitznig A, Bernthaler A, Dolznig H, Sommergruber W
      PLoS ONE, 0;10(4):e0124283.
      Species: Human
      Sample Type: Cell Culture Supernates
    Expand to show all 229 Citations
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     Human IL-8/CXCL8 Quantikine ELISA Kit D8000C
    : Human IL-8/CXCL8 Quantikine ELISA Kit [D8000C]

    Summary

    Sample TestedA375 human melanoma cell line

    Other Experimental Details

    Other Experimental DetailsSupernatents of A375-MA2 treated with siCtrl or siIL-8 were assessed using IL-8 ELISA (R&D).

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