Human INSL6 Antibody

Catalog # Availability Size / Price Qty
MAB4430
MAB4430-SP

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Human INSL6 Antibody Summary

Species Reactivity
Human
Specificity
Detects human INSL6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) INSL3 and rhINSL4 is observed.
Source
Monoclonal Rat IgG2A Clone # 421401
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human INSL6
Arg21-Tyr213
Accession # Q9Y581
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human INSL6

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: INSL6

Insulin-like 6 (INSL6) is a member of the insulin family that is expressed in the testis by germ cells in the seminiferous tubules. Intracellular INSL6 is processed to a complex of two disulfide-linked peptides for secretion. Human and mouse INSL6 share 43% aa identity in the 213 aa, 28 kDa unprocessed form and 53% aa identity in the 64 aa, 8 kDa processed form.

Long Name
Insulin-like 6
Entrez Gene IDs
11172 (Human); 27356 (Mouse); 50546 (Rat)
Alternate Names
INSL6; Insulin-Like 6; Insulin-like peptide 5; Insulin-Like Peptide 6; Insulin-Like Peptide INSL6; Relaxin/Insulin-Like Factor 1; RIF1

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