Human Integrin  beta 7 Antibody

Catalog # Availability Size / Price Qty
Detection of Integrin  beta 7 in Human Lymphocytes by Flow Cytometry.
1 Image
Product Details
Supplemental Products

Human Integrin  beta 7 Antibody Summary

Species Reactivity
Detects human Integrin  beta 7 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant mouse Integrin  beta 7 is observed and less than 1% cross-reactivity with recombinant human (rh) Integrin  beta 2, rhIntegrin  beta 5, and rhIntegrin  beta 6 is observed.
Polyclonal Sheep IgG
Antigen Affinity-purified
Chinese hamster ovary cell line CHO-derived recombinant human Integrin beta 7 long isoform
Accession # P26010
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Human Integrin  beta 7
Flow Cytometry
0.25 µg/106 cells
See below
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of Integrin  beta 7 antibody in Human Lymphocytes antibody by Flow Cytometry. View Larger

Detection of Integrin beta 7 in Human Lymphocytes by Flow Cytometry. Human blood derived lymphocytes were stained with Human Integrin beta 7 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4669, filled histogram) or isotype control antibody (Catalog # 5-001-A, open histogram), followed by NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # NL010).

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Integrin beta 7

Human Integrin beta 7 (also Integrin beta P and M290 IEL Ag) is a 120 kDa member of the Integrin beta chain family of molecules. It is a type I transmembrane glycoprotein that contains a 704 amino acid (aa) extracellular domain (ECD) (aa 20-723) and a 52 aa cytoplasmic tail. The ECD contains one von Willebrand factor A domain (aa 150-389) and four cysteine-rich EGF-like repeats. One splice variant exists that shows a deletion of aa 501-648. Integrin  beta 7 forms a nondisulfide linked heterodimer with  alpha 4 and  alpha E integrins. alpha 4 beta 7 binds fibronectin, VCAM-1, and MADCAM1, while alpha E beta 7 binds E-cadherin. The ECD of human  beta 7 is 87% aa identical to the ECD of mouse  beta 7.

Entrez Gene IDs
3695 (Human); 16421 (Mouse); 25713 (Rat); 102137082 (Cynomolgus Monkey)
Alternate Names
Gut homing receptor beta subunit; integrin beta 7 subunit; Integrin beta 7; integrin beta-7; integrin, beta 7; ITGB7

Product Datasheets

You must select a language.



No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Reviews for Human Integrin  beta 7 Antibody

There are currently no reviews for this product. Be the first to review Human Integrin  beta 7 Antibody and earn rewards!

Have you used Human Integrin  beta 7 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review