Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Sheep IgG
View all ISLR-2 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human ISLR-2
Cys20-Leu590
Accession # Q6UXK2

Specificity

Detects human ISLR-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant human ISLR-2 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for Human ISLR‑2 Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human ISLR‑2

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: ISLR-2

ISLR-2 (Ig-superfamily containing LRR protein 2; also KIAA1465) is a 100‑110 kDa member of the LRR family of proteins. It is expressed on developing motor, sensory and interneurons. Mature human ISLR-2 is 727 amino acids (aa) in length. It is a type I transmembrane glycoprotein that contains a 571 aa extracellular domain (ECD) and a 135 aa cytoplasmic region. The ECD shows multiple LRRs (aa 50‑227) and one Ig-like domain (aa 233‑371). One alternate splice form may exist that shows a deletion of aa 160‑570. Over aa 20‑590, human ISLR-2 is 89% aa identical to both canine and mouse ISLR-2.

Long Name

Immunoglobulin Superfamily Containing Leucine-rich Repeat 2

Alternate Names

ISLR2

Entrez Gene IDs

57611 (Human); 320563 (Mouse)

Gene Symbol

ISLR2

UniProt

Q6UXK2

Additional ISLR-2 Products

Product Documents for Human ISLR‑2 Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human ISLR‑2 Antibody

For research use only

Related Research Areas

Immunoglobulin Superfamily CAMs

Citations for Human ISLR‑2 Antibody

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