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Human MGMT Primer Pair

Catalog #: RDP-126 Datasheet / COA / SDS

Discontinued Product

RDP-126 has been discontinued.
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Human MGMT Primer Pair Summary

Specifications

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Human

Product Datasheets

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Product Datasheet
COA

Background: MGMT

The O-6-methylguanine-DNA-methyl transferase (MGMT) is involved in the direct repair of DNA alkylated at the O6 position of guanine. MGMT transfers the alkyl group to its own cysteine thereby inactivating the MGMT molecule. Therefore, the number of MGMT molecules correlates directly with the cell's ability to withstand DNA alkylation.

Long Name
O-6 Methylguanine-DNA Methyltransferase
Entrez Gene IDs
4255 (Human); 17314 (Mouse)
Alternate Names
6-O-methylguanine-DNA methyltransferase; EC 2.1.1.63; methylated-DNA--protein-cysteine methyltransferase; methylguanine-DNA methyltransferase; MGMT; O-6-methylguanine-DNA methyltransferase; O6-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase

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