Human/Mouse c-Myc Alexa Fluor® 700-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: c-Myc

Human c-Myc is a 439 amino acid transcription factor with a bHLH/LZ (basic Helix-Loop-Helix, Leucine Zipper) domain. c-Myc DNA-binding and transcription function is achieved upon heterodimerization with its partner Max. c-Myc is often over-expressed and mutated in hematopoietic tumors. Mutations frequently result in truncations that remove the transactivation region or in the bHLH/LZ domain required for association with Max and DNA. Over the region used as immunogen, human c-Myc is 92% identical to the rat and mouse c-Myc proteins.

Product Datasheets

Related Research Areas

• Apoptosis Transcription Factors and Regulators
• Basic Helix-Loop-Helix (bHLH) Transcription Factors
• Basic Leucine Zipper (bZIP) Transcription Factors
• Cancer Biomarkers
• Cancer Stem Cell Markers
• Cancer Stem Cell Transcription Factors
• Cell Cycle
• DNA Damage and Repair
• Embryonic and Induced Pluripotent Stem Cell Markers
• Epithelial Stem Cell Transcription Factors
• Hematopoietic Stem Cell Transcription Factors and Regulators
• Natural Killer T (NKT) Cells
• Pluripotent Stem Cell Transcription Factors
• Transcription Factors in the Akt Pathway