Osteocrin Antibody (311413)

R&D Systems | Catalog # MAB26201

R&D Systems

Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 311413
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Product Specifications

Immunogen

E. coli-derived recombinant mouse Osteocrin
Val28-Gly130
Accession # P61364

Specificity

Detects only the pro form (11 kDa) of human and mouse Osteocrin in direct ELISAs and Western blots.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Osteocrin Antibody (311413)

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Mouse Osteocrin

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.


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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Osteocrin

Mouse Osteocrin, also known as Musclin, is a secreted protein that is primarily expressed in bone and muscle. It is synthesized as a proprotein (11 kDa) that undergoes proteolytic processing to generate a mature 50 amino acid 5 kDa C-terminal active peptide. It was found to modulate osteoblast differentation and to regulate glucose metabolism in muscles. Mouse Osteocrin proprotein shares 77% and 78% amino acid sequence identity with the rat and human protein, respectively.

Alternate Names

Musclin, OSTN

Entrez Gene IDs

344901 (Human); 239790 (Mouse)

Gene Symbol

OSTN

UniProt

Additional Osteocrin Products

Product Documents for Osteocrin Antibody (311413)

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Osteocrin Antibody (311413)

For research use only

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