Human/Mouse PARP Alexa Fluor® 532-conjugated Antibody Summary
Val71-Pro329
Accession # NP_031441
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
Background: PARP
PARP, Poly [ADP-ribose] polymerase 1 (PARP1), is a component of a base excision repair (BER) complex, containing at least XRCC1, PARP2, POLB and LRIG3. Widely expressed. Expression is correlated with proliferation, with higher levels occurring during early fetal development and organogenesis and in the highly proliferative cell compartments of adult. Expressed in B-cells that have been induced to switch to various Ig isotypes. PARP interacts with the DNA polymerase alpha catalytic subunit POLA1; this interaction functions as part of the control of replication fork progression.
Product Datasheets
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