Human/Mouse/Rat PDCD5 Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB7325N Datasheet / COA / SDS

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FAB7325N-100UG

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Human/Mouse/Rat PDCD5 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human, Mouse, Rat

Specificity

Detects human PDCD5 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human PDCD6 is observed.

Source

Monoclonal Mouse IgG1 Clone # 728906

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human PDCD5
Ala2-Tyr125
Accession # O14737

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PDCD5

PDCD5 (programmed cell death 5), also called TFAR19 (TF-1 cell apoptosis-related 19) is a ubiquitously expressed, approximately 15 kDa protein that is upregulated during apoptosis and downregulated in many cancer cell types. Of its 124 amino acids (aa), 44 are acidic or basic. PDCD5 also contains two acetylated aa and one constitutively phosphorylated aa, S119, which is involved in promoting apoptosis. Human PDCD5 shares 95% and 96% aa sequence identity with mouse and rat PDCD5, respectively.

Long Name

Programmed Cell Death 5

Entrez Gene IDs

9141 (Human); 56330 (Mouse); 292814 (Rat)

Alternate Names

FLJ42784; MGC9294; PD5; PDCD5; programmed cell death 5; programmed cell death protein 5; Protein TFAR19; TF-1 cell apoptosis-related protein 19; TFAR19 novel apoptosis-related; TFAR19; TFAR19TF1 cell apoptosis-related gene 19