Human/Mouse TL1A/TNFSF15 Antibody

Catalog # Availability Size / Price Qty
MAB7441
MAB7441-SP

Save Up to 40% on RUO Reagents with BIOSPRING24 (See Details)

Product Details
Citations (3)
FAQs
Supplemental Products
Reviews (2)

Human/Mouse TL1A/TNFSF15 Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects mouse TL1A/TNFSF15 in direct ELISAs and Western blots. Shows 100% cross-reactivity with recombinant human TL1A.
Source
Monoclonal Rat IgG1 Clone # 293327
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant mouse TL1A/TNFSF15
Ile94-Leu270
Accession # NP_796345.3
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human TL1A/TNFSF15 (Catalog # 1319-TL)
Recombinant Mouse TL1A/TNFSF15 (Catalog # 1896-TL)
Neutralization
Reichwald, K. et al. (2014) PLoS ONE. 9:e85793.
Reichwald, K. et al. (2014) PLoS ONE. 9:e105627.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Loading...
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TL1A/TNFSF15

TL1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNFSF15. It is expressed predominantly in endothelial cells, and its expression is inducible by TNF-alpha and IL-1 alpha. TL1A binds with high affinity to DR3/TNFRSF25 on activated T cells.

Long Name
TNF-like 1
Entrez Gene IDs
9966 (Human); 326623 (Mouse)
Alternate Names
MGC129934; MGC129935; TL1A; TL1Vascular endothelial cell growth inhibitor; TNF superfamily ligand TL1A; TNFSF15; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand superfamily member 15; vascular endothelial growth inhibitor-192A; VEGI; VEGI192A; VEGITNF ligand-related molecule 1

Product Datasheets

You must select a language.

x

Citations for Human/Mouse TL1A/TNFSF15 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
Filter your results:

Filter by:

  1. The TL1A-DR3 Axis Selectively Drives Effector Functions in Human MAIT Cells
    Authors: A Sattler, LG Thiel, AH Ruhm, N Souidi, M Seifert, G Herberth, K Kotsch
    J. Immunol., 2019-10-18;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  2. ROR?-expressing T regulatory cells restrain allergic skin inflammation
    Authors: N Malhotra, JM Leyva-Cast, U Jadhav, O Barreiro, C Kam, NK O'Neill, F Meylan, P Chambon, UH von Andria, RM Siegel, EC Wang, R Shivdasani, RS Geha
    Sci Immunol, 2018-03-02;3(21):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  3. TL1A induces TCR independent IL-6 and TNF-alpha production and growth of PLZF(+) leukocytes.
    Authors: Reichwald K, Jorgensen T, Tougaard P, Skov S
    PLoS ONE, 2014-01-08;9(1):e85793.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs
Loading...

Reviews for Human/Mouse TL1A/TNFSF15 Antibody

Average Rating: 3.5 (Based on 2 Reviews)

5 Star
0%
4 Star
50%
3 Star
50%
2 Star
0%
1 Star
0%

Have you used Human/Mouse TL1A/TNFSF15 Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Human/Mouse TL1A/TNFSF15 Antibody
By Anonymous on 11/15/2017
Application: ELISA Sample Tested: HEK293 human embryonic kidney cell line Species: Human

Human/Mouse TL1A/TNFSF15 Antibody
By Anonymous on 07/17/2017
Application: WB Sample Tested: Recombinant protein Species: Human

Use for detection of TL1A in a sandwich ELISA (2.5ug/mL concentration), and for detection of recombinant TL1A in Western blots at a 1:1000 dilution, followed by a Licor secondary antibody.