Human/Mouse TL1A/TNFSF15 Antibody

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Product Details
Citations (3)
Supplemental Products
Reviews (2)

Human/Mouse TL1A/TNFSF15 Antibody Summary

Species Reactivity
Human, Mouse
Detects mouse TL1A/TNFSF15 in direct ELISAs and Western blots. Shows 100% cross-reactivity with recombinant human TL1A.
Monoclonal Rat IgG1 Clone # 293327
Protein A or G purified from hybridoma culture supernatant
E. coli-derived recombinant mouse TL1A/TNFSF15
Accession # NP_796345.3
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
1 µg/mL
Recombinant Human TL1A/TNFSF15 (Catalog # 1319-TL)
Recombinant Mouse TL1A/TNFSF15 (Catalog # 1896-TL)
Reichwald, K. et al. (2014) PLoS ONE. 9:e85793.
Reichwald, K. et al. (2014) PLoS ONE. 9:e105627.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TL1A/TNFSF15

TL1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNFSF15. It is expressed predominantly in endothelial cells, and its expression is inducible by TNF-alpha and IL-1 alpha. TL1A binds with high affinity to DR3/TNFRSF25 on activated T cells.

Long Name
TNF-like 1
Entrez Gene IDs
9966 (Human); 326623 (Mouse)
Alternate Names
MGC129934; MGC129935; TL1A; TL1Vascular endothelial cell growth inhibitor; TNF superfamily ligand TL1A; TNFSF15; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand superfamily member 15; vascular endothelial growth inhibitor-192A; VEGI; VEGI192A; VEGITNF ligand-related molecule 1

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Citations for Human/Mouse TL1A/TNFSF15 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. The TL1A-DR3 Axis Selectively Drives Effector Functions in Human MAIT Cells
    Authors: A Sattler, LG Thiel, AH Ruhm, N Souidi, M Seifert, G Herberth, K Kotsch
    J. Immunol., 2019-10-18;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  2. ROR?-expressing T regulatory cells restrain allergic skin inflammation
    Authors: N Malhotra, JM Leyva-Cast, U Jadhav, O Barreiro, C Kam, NK O'Neill, F Meylan, P Chambon, UH von Andria, RM Siegel, EC Wang, R Shivdasani, RS Geha
    Sci Immunol, 2018-03-02;3(21):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  3. TL1A induces TCR independent IL-6 and TNF-alpha production and growth of PLZF(+) leukocytes.
    Authors: Reichwald K, Jorgensen T, Tougaard P, Skov S
    PLoS ONE, 2014-01-08;9(1):e85793.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization


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Reviews for Human/Mouse TL1A/TNFSF15 Antibody

Average Rating: 3.5 (Based on 2 Reviews)

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Human/Mouse TL1A/TNFSF15 Antibody
By Anonymous on 11/15/2017
Application: ELISA Sample Tested: HEK293 human embryonic kidney cell line Species: Human

Human/Mouse TL1A/TNFSF15 Antibody
By Anonymous on 07/17/2017
Application: WB Sample Tested: Recombinant protein Species: Human

Use for detection of TL1A in a sandwich ELISA (2.5ug/mL concentration), and for detection of recombinant TL1A in Western blots at a 1:1000 dilution, followed by a Licor secondary antibody.