Human MS4A3 PE-conjugated Antibody

  • Species Reactivity
  • Specificity
    Detects human MS4A3 in direct ELISAs.
  • Source
    Monoclonal Mouse IgG2A Clone # 489433
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    NS0 mouse myeloma cell line transfected with human MS4A3
    Accession # NP_006129
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of MS4A3 in Human Whole Blood Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Mouse Anti-Human MS4A3 PE‑conjugated Monoclonal Antibody (Catalog # FAB6247P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: MS4A3

MS4A3, also known as HTm4, is an membrane protein that is a member of the MS4A family of four-transmembrane proteins that also includes CD20 and Fc epsilon RI beta.  MS4A3 is a cell cycle regulator expressed in the perinuclear area of human basophils, eosinophils, early embryonic neural progenitors, splenic red pulp macrophages, monocytes and bile duct plus pancreatic duct epithelium. The C-terminal region of MS4A3 interacts with cdc-associated phosphatase (KAP), enhancing its activity on cyclin-dependent kinase 2 (cdk2) and facilitating G(0)/G(1) arrest. The combined non-membrane segments of the 214 amino acid (aa), 22-25 kDa human MS4A3 show 53% and 52% aa identity with corresponding regions of mouse and rat MS4A3, respectively.

  • Long Name:
    Membrane-spanning 4-domains, Subfamily A, Member 3 [Hematopoietic Cell-specific]
  • Entrez Gene IDs:
    932 (Human); 170813 (Mouse); 293753 (Rat)
  • Alternate Names:
    CD20 antigen homolog; CD20 antigen-like protein; CD20L; CD20LIgE receptor beta subunit; hematopoietic cell 4 transmembrane protein; Hematopoietic-specific transmembrane protein 4; HTM4; HTM4IgE receptor beta chain; membrane-spanning 4-domains subfamily A member 3; membrane-spanning 4-domains, subfamily A, member 3 (hematopoieticcell-specific)
Related Research Areas
Isotype Controls
Description Application Cat# Citations Images  

Mouse IgG2A PE-conjugated Antibody

Ctrl IC003P 10  
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Staining Reagents
Description Application Cat# Citations Images  

Flow Cytometry Staining Buffer (1X)

Flow FC001 3
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Flow Cytometry Mouse Lyse Buffer (10X)

Flow FC003 1
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Flow Cytometry Human Lyse Buffer (10X)

Flow FC002 1
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