Human Opticin Antibody
Human Opticin Antibody Summary
Accession # Q9UBM4
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Opticin (Oculoglycan) is a member of the small leucine-rich proteoglycan (SLRP) family with homology to class III extracellular matrix family members Epiphycan and Mimecan. It forms a 90 kDa noncovalent dimer that is a component of vitreous collagen fibrils in the eye and is also expressed in the retina, iris, ligaments and skin. Mature human Opticin shares 73% and 65% aa identity with mouse and rat, respectively. Mutations of Opticin have been associated with age-related macular degeneration.
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